for 3rd exam
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| which drug is the top psychiatric perscription? | Xanax, then lexapro, Zoloft, Prozac
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| categories of psychiatric drugs (7) | Antipsychotic, anti-cholinergic, antidepressant, antimanic, antianxiety, anti-obsessional, CNS stim
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| Dopamine | neurotransmitter assoc w/schizophrenia, increased - mania, schizo; decreased = depression, P symptoms
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| Nor-epinephrine | UP: mania, anxiety states, schizo; DOWN: depression
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| Serotonin | UP: anxiety state
DOWN: depression
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| GABA | UP: reduced anxiety; DOWN: anxiety do, schizo
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| Acetylcholine | UP: depression: Down: P, Alzheimer's, Huntington's chorea
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| Abilify, Seoquel, Zyprexia, Respiridal | antipsychotic drug names - atypical
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| uses for antipsychotics | acute psychosis, schizophrenia, psychotic depression, bipolar do, dementia w/agitation
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| Which psychotic drugs were used to treat POSITIVE symptoms? | 1st generation, standard like MOA, anti-cholinergic's
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| What is a positive symptom? | anything that is there that SHOULD NOT be there
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| What is a negative symptom? | Something that is NOT there but SHOULD BE there
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| What is a EPS- extrapyramidal Side Effect | Various movement disorders like acute dystonia, invol spasms, tics, akinesia, akathisia, P syndrome
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| Akithisia | restless legs, tapping feet
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| Tardive Dyskinesia | (Rose) - caused by LT use of 1st Gen antipsychotics. invol mouse movements, blinking, chewing, - irreversible
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| Neuroleptic Malignant Syndrome | most lethal side effect of antipsychotic: onset within hrs to years of Tx - thermoregulator system goes haywire, photosensitivity
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| Atypical/2nd general antipsychotics | work on negative & positive symptoms of schizophrenia, few to no EPS, sedation, excessive salivation, nausea, wt gain
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| How 2nd gen antipsychotics work | block both dopamine & seratonin
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| most prescribed antipsychotic | Abilify, - approved to tx bipolar too
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| clozaril agranulocytosis | a potentially fatal reaction from clozaril (used in most severe cases) - drop in WBC, fever onset, risk of infection - sore throat WARNING
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| Side effect comparison of 1st w/ 2nd generation of antipsychotics | OLD - movement do
NEW - metabolism issues
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| What are anti-cholinergic medications & why used? | Used to counteract side effects of anti psychotic meds
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| Tricyclic anti-depressants - eg | Elavil, anafranil, sinequan
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| MAOIs: | Parnate, Nardil, Saphra
not used b/c interactions with digestion
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| SSRI - selective serotonin reuptake inhibitors | Paxil, Prozac, Zoloft, Celexa, Lexapro - the first of the New class of drugs
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| Atypical anti-depressants | effexor, wellbutrin (smoking); Pristiq, Cymbalta, Remeron
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| Which anti-depressanta (atypical) are most prescribed? | SSRIs
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| pros of SSRIs | can't OD, good for non-compliant pt, also used for anti anxiety, chronic pain, PMS, PMDD
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| which SSRIs act quickly | Celexa and Lexapro
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| Dangerous interactions with SSRIs | Don't take with MAOIs - serotonin syndrome - too much builds (hyperthermia, muscle rigidity, myoclonus, rapid change in mental status)
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| How long should you wait after stopping one kind of anti-depressant before beginning another? | 6 weeks
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| TCA - tricyclic antidepressants side effects | dry mouth, constipation, blurred vision, metallic taste, urine retention, orthostatic hypotension, drowsiness, weight gain
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| Most serious danger of TCAs | cardiac toxicity - due to increase of norinepinephrine in hear
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| what is a MAOI diet? | no cheese, alcohol, cured meat, fermented items, vinegar
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| Dangers of lithium | narrow window of therapuetic level - early toxicity, can kill if above 2.0, changes conductivity of heart, depresses respiration, renal function, keep hydrated!
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| What are Benzodiazipines? | drugs for antianxiety - potentiates actions of GABA (-pam ending)
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Created by:
sherryama
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