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HIV

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Question
Answer
HIV   Human Immunodeficiency Virus  
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AIDS 2   -Acquired Immunodeficiency Syndrome -Disease of HIV  
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Define bacteria   -Able to reproduce independently, so living organism -Snsitive to anti biotic  
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Define Virus   -not living organism -Require host cell -Anti-bio does not work  
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STD is Virus or Bacterial infection?   Bacteria Infection  
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2 STD disease   -Syphilis -Gonorrhea  
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Syphilis   Bacterium; Treponema pallidum  
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Gonorrhea   Bacterium; Neisseria gonorrhoeae  
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Examples of DNA containing viruses   -Herpes -Small pox -Hepatitis B -Adenovirus  
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Do viruses have organelle?   NO  
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Which one is STD? -Herpes -Small pox -Hepatitis B -Adenovirus   Herpes  
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Which one attack lung cell? -Herpes -Small pox -Hepatitis B -Adenovirus   Adenovirus  
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Examples of RNA containing viruses   -Hepatitis A&C -Rabies -Ebola -Measles -Mumps -Polio -HIV  
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Define Retro-vial Replication   Conversion of host cell to DNA  
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Are all RNA containing virus Retro-virus?   NO  
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Define reverse transcription   RNA from HIV virus to Viral DNA  
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Explain Retro-vial Replication   p.2  
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What is the primary host cell of HIV?   Lymphocytes (WBC)  
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2 types of Lymphocytes   B & T  
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2 Types of T-Lymphocytes   -Cytotoxic T-cell -Helper T cell  
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What is the primary target of HIV?   Helper T cell [infection of T cell cause AIDS]  
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The name of the receptor of Helper T cells   CD 4  
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Reverse transcriptase   Enzyme that convert RNA to DNA  
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Integrase   Retro-viral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that enables its genetic material to be integrated into the DNA of the infected cell.  
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Incubation   潜伏  
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Define pro-virus   DNA sequence that originated through the process of transcription and integrated human genome  
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Latent   inactive  
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Lytic   activated  
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Reverse transcriptase is also called?   Error- Pione  
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2 Co-receptors   CCR5, CXCR4  
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Helper cell attaches to ?   Gp 120  
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3 HIV gene of pro-virus   env, gag, pol  
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Env gene   Responsible for glyco protein on surface  
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Gag gene   Responsible for protein in the capsle  
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Pol gene   Responsible for one of 3 different enzymes  
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How does virus remake itself?   Carry the gene with it that can reproduce the structure of the enzyme, shell, glycoprotein  
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Define budding   -Virus is being released from cell -Virus particle surround themselves with a layer of host cell membrane & bud off from the surface fo the host cell  
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Non-human primate   Simian  
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Virus that is found in animals, Chimpanzee   Simian immune deficiency virus (SIV cpz)  
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Simian virus from Pan troglodytes troglodytes is almost identical to ?   HIV 1  
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Simian virus from Sooty mangabey monkey is corresponds to ?   HIV 2  
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When proviral DNA is activated, it is called   Lytic stage  
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When proviral DNA is stored, it is called   Lysogenic stage  
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Steps of infection 4   1.Vral RNA 2.Infects Helper T-cell 3.Integrates into host DNA 4.Proviral DNA  
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CRF's, Recombination   process by which a molecule of nucleic acid (usually DNA, but can also be RNA) is broken and then joined to a different one.  
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