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Pathology

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term
definition
adeno   gland  
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anisokaryosis   inequality in the size of the nuclei of cells  
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atrophy   decrease in the size of a tissue or organ  
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benign   not recurrent  
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carcinoma   malignant, invasive growth of epthelial cells  
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congenital   born with  
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edema   accumulatin of fluid in the cavities and intraceullular spaces  
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endogenous   from within  
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exogenous   from without  
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exudate   fluid with a high content of protein and cellular debris  
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hyperplasia   increase in the # of cells  
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hypertrophy   increase in the size of cells  
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iatrogenic   disease caused by Tx  
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idopathic   unknown cause  
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ischemia   deficiency of blood flow due to functional constriction or obstruction of a blood vessel  
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malignant   recurrent and worsening  
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metastatsis   transfer of disease from organ to organ  
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multicentric   same pathological lesion occuring in many different sites at the same time  
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necropsy   exam of the body after death  
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necrosis   morphological changes indicative of cell death by enzymatic degradation  
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neoplasm   any new and abnormal growth in which cell multiplication is uncontrolled and progressive  
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oma   tumor or neoplasm  
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oncology   study of tumors  
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pathology   structural and functional manifestation of a disease  
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pica   eating foreign/non-food items  
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pleomorphism   having more then one shape or form  
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sarcoma   highly malignant tumor derived from connective tissue  
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systemic   pertaining to or affecting the body as a whole  
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etiology   study of the cause of a disease  
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epidemiologic triangle   host, disease, environment, (controlled by husbandry management)  
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disease causes overview   infectious agents (bacteria etc.); Nutritional issues; (Dehydration); genetic, congenital, environmental, allergic  
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disease causes, agents   venom, neoplasia, AI disease, trauma, toxins, degenerative conditions (arthritis), iatrogenic, idiopathic  
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disease state   acute, chronic, subclinical, latent  
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oncology   study of cancer  
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phagocytes   neutrophils and monocytes  
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leukocytes   WBC  
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Cancer Tx   surgery, radiotherapy, chemotherapy, immunotherapy, alternative, cryotherapy, phototherapy  
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CNS   Central Nervous System  
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Benign   does not destroy tissue  
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malignant   destroys tissue, metastasize  
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Lymphoma   Assoc with FELV, FIV, can appear in any organ, 80% of lymphoma in dogs multcentric  
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Chemotherapy   used for systemic or metastatic cancers; post-op; pre-op Tx to reduce tumors  
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Chemo agents   Alkylating agents, antimetabolites, antitumor antibiotics, Plant alkaloids, Hormones, Misc. (tox plant alkaloids in order of toxicity vincristin, vinblastin, etoposide)  
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Oropharyngeal   Malignant melanoma, fibrosarcomas, squamous cell carcinoma - The oropharynx is the middle part of the pharynx (throat) behind the mouth, and includes the back one-third of the tongue, the soft palate, the side and back walls of the throat, and the tonsils  
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Hemangiosarcoma   Originate in vascular endothelium, 50% in spleen, 40% in right atrium  
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Osteosarcoma   Bones, aggressive  
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mast cell tumor   Mastocytoma, mast cell sarcoma  
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Grade 1   well differentiated mast cell  
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Grade 2   moderately differentiated mast cell  
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Grade 3   poorly differentiated mast cell  
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fine needle aspirate   small needle, large syringe  
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punch biopsy   sedation, surgical prep  
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tru-cut biopsy   sedation, surgical prep, ultrasound  
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mediastinal   or affecting the mediastinum-lungs, heart, trachea, connective tissue, thymus gland  
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Alimentary   GI, multifocal, diffused  
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Extranodal   Any organ but Lymp - extranodal internal organs such as thyroid, salivary glands, or stomach that are still confined to the organs where they started  
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fomite   inanimate object or material on which disease prod agents maybe conveyed  
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vector   a carrier which transfers an infectious agent  
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biological vector   an animal that transforms a disease prior to transfer (growth)  
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mechanical vector   object/animal that does not affect the lifecycle of disease or parasite before transmitl  
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Host factors   immune status, vaccinations, age gender, behavior, repor status, genetics  
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disease prod agents   concentration or hardiness, virulence, toxicity  
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environment   density of stock, movement between animal groups, housing, environ conditions, nutrition  
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contagious   one capable of being transmiotted from animal to animal  
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infectious   one that is caused by or capable of being communicated by infection  
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traumatic   wound or injury  
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genetic   inherited  
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toxic   poisonous  
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infections   bacteris, fungus, fungi, protozoa, parasite  
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nutritional   deficiences or excess of fat soluble vitamins, starvation, dehydration  
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congenital   present from birth  
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environmental cause   e. coli, housing, temperature, pollution  
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allergic cause   contact dermitis, vaccines, drugs, food, environ  
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neoplasia   formation of tumors, any new and abnormal growth  
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autoimmune   AIHA immune response to own body  
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degenerative   deterioration occurs producing less functionality in tissues or organs  
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iatrogenic   caused by Tx  
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idiopathic   unknown  
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inflammation signs   heat, redness, swelling, pain, loss of function  
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exudates   serous, hemorrhagic, serosanguinous, purulent, mucopurulent  
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healing stages   removal repair regenration  
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highest regeneration   connective tissues, blood, vessels, epithelium, blood forming tissues  
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lowest regeneration   CNS tissues  
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protective mechanism   outer epithelium, secretions, MM, Internal anatomy (cilia) phagocytes  
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prevention   healthy environ, increasing host resistance (vaccines, food, etc)  
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