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Module 2 - Rh

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Question
Answer
Haplotype R1 is composed of what Gene locus(i) and antigens   Loci: RHD, RHCe Antigens: D, C, e  
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Haplotype R2 is composed of what Gene locus(i) and antigens   Loci: RHD, RHcE Antigens: D, c, E  
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Haplotype Rz is composed of what gene locus(i) and antigens   loci: RHD, RHCE Antigens: D, C, E  
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Haplotype r' is composed of what gene locus(i) and antigens   locus: RHCe Antigens: C, e  
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Haplotype r'' is composed of what gene locus(i) and antigens   locus: RHcE Antigens: c, E  
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Haplotype r(y) is composed of what gene locus(i) and antigens   locus: RHCE Antigens: C, E  
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Haplotype r is composed of what gene locus(i) and antigens   locus: RHce Antigens: c, e  
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Haplotype R(o) is composed of what gene locus(i) and antigens   locus: RHD, RHce Antigens: c, e  
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Most D to least D antigen haplotypes   ↑ R2R2, R1R2, R1R1, R2r, Ror, R1r ↓  
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Frequency of D antigen in White and Black population   White 85% , Black 92%  
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Frequency of C antigen in White and Black population   White 70% , Black 27%  
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Frequency of E antigen in White and black population   White 30% , Black 22%  
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Frequency of c antigen in White and Black population   White 80% , Black 96%  
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Frequency of e antigen in White and Black population   White 98% , Black 98%  
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Haplotype   Inherited allele from 1 parent  
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Genotype   Inherited haplotypes (from both parents)  
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Most probable genotype (MPG)   Determined from typing results, haplotype frequencies and family studies  
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Phenotype   Derived from cell typing results – Often symbolized as the most probable genotype  
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