OTIC
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| Lubricant drops (OTC) Brand name | *Lacri-tears *Genteal *Opti-tears *Tears
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| Lubricant drops (OTC) dose | 1-2 drops into affected eye QD to prn
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| Lubricant drops (OTC) MOA | Acts like mucin and stabilize tear film to reduce evaporation
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| Lubricant drops (OTC) common SE | Crusting on eyelids, allergy to preservative
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| Lubricant ointments (OTC) ingredients | White petrolatum, Mineral oil, Anhydrouslanolin, Hydroxypropylcellulose
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| Lubricant ointments (OTC) dosing | Apply QD (often at bedtime) to prn
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| Lubricant ointments (OTC) MOA | Acts like mucin and stabilize tear film to reduce evaporation
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| Lubricant ointments (OTC) SE | Blurred vision
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| Mast cell stabilizer (Rx) Brands | Opticrom, Crolom,Alomide,Alamast,Alocril
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| Mast cell stabilizer (Rx) Ingredients | Cromolyn 4%,Lodoxamide 0.1%, Pemirolast 0.1%,Nedocromil 2%,
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| Opticrom, Crolom dosing | 1 drop 4-6 times per day and then taper to BID as symptoms improve
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| Alomide dosing | 1-2 drops QID for up to 3 months
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| Alamast dosing | 1-2 drops BID-QID
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| Alocril dosing | 1-2 drops BID
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| Mast cell stabilizer (Rx) MOA | Decrease the degranulation of mast cells and prevent the release of inflammatory mediators
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| Mast cell stabilizer (Rx) SE | HA, ocular burning/stinging, rhinitis
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| Antihistamine (Rx) Brand names | Livostin, Emadine
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| Antihistamine (Rx) dosing | 1 drop in each eye BID-QID
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| Antihistamine (Rx) MOA | Relatively to highly selective H1 receptor antagonists
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| Antihistamine (Rx) SE | Burning, stinging upon instillation; mydriasis, HA
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| Decongestant (OTC) Ingredients | Naphazoline HCl, Tetrahydrozoline, Phenylephrine,Oxymetazoline HCl
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| Decongestant (OTC) dosing | 1-2 drops in each eye QD-QID for all four agents
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| Decongestant (OTC) MOA | Vasoconstriction to reduce redness, vascular congestion, eyelid edema
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| Decongestant (OTC) SE | Conjunctivitis medicamentosa, stinging upon instillation, mydriasis
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| NSAIDS (Rx) Brand | Acular
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| NSAIDS (Rx) dosing | 1 drop in affected eye(s) QID up to 7 days
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| NSAIDS (Rx) MOA | Inhibit COX, decreasing prostaglandins
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| NSAIDS (Rx) SE | Hypersensitivity, transient burning/stinging (40%), dry eye, ocular infections, visual disturbancesCI: Pregnant women (3rd trimester)
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| Steroids (Rx) Brand | Decadron, Maxidex, Pred Mild, FML,HMS, Lotemax, Alrex, Vexol
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| Steroids (Rx) Dosing | 1 drop TID-QID Note: you may see 1 drop of the ophthalmic solution q hour while awake x 1 week and then reduced for severe cases
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| Steroids (Rx) MOA | Decrease production of prostaglandins and leukotrienes
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| Steroids (Rx) SE | Increased intraocular pressure (glaucoma), cataracts, predisposition to ocular infection, blurred vision, dry eye
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| Antihistamine and Mast Cell Stabilizer (Rx) Brand | Patanol, Zaditor
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| Antihistamine and Mast Cell Stabilizer (Rx) Dosing | 1-2 drops BID (space by 6-8 hours)
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| Antihistamine and Mast Cell Stabilizer (Rx) MOA | H1 receptor antagonism and mast cell stabilization
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| Antihistamine and Mast Cell Stabilizer (Rx) SE | Stinging upon administration and headache.
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| AntihistamineMast Cell Stabilizer, and Eosinophil inhibitor (Rx) Brand | Optivar, Zaditor
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| AntihistamineMast Cell Stabilizer, and Eosinophil inhibitor (Rx) MOA | H1 receptor antagonism, mast cell stabilization, and direct inhibitory effect on eosinophil chemotaxis and degranulation
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| AntihistamineMast Cell Stabilizer, and Eosinophil inhibitor (Rx) SE | Conjunctival infection, HA, rhinitis, burning/stinging, bitter taste
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| Antihistamine and Decongestant (OTC) Brand | Naphcon A, Opcon-A, Vasocon-A
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| Antihistamine and Decongestant (OTC) dosing | 1-2 drops in each eye BID-QID
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| Antihistamine and Decongestant (OTC) MOA | H1 receptor antagonism and Vasoconstriction to reduce redness, vascular congestion, eyelid edema
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| Antihistamine and Decongestant (OTC) SE | Burning, stinging upon instillation; mydriasis, HA, conjunctivitis medicamentosa, stinging upon instillation
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| Antiviral (Rx) Brand | Viroptic
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| Antiviral (Rx)- Viroptics generic name | Trifluridine
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| Antiviral (Rx) Dosing | 1 drop q2h while awake (9 drops max/day) until healed ulcer, then 1 drop q4h (5 drops max/day) x 7 more days not to exceed 21 days of therapy
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| Antiviral (Rx) MOA | Inhibit DNA synthesis by inhibiting thymidylic phosphorylase which is needed for the incorporation of thymidine into the viral DNA
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| Antiviral (Rx) SE | Burning, corneal edema, punctate lesions in corneal epithelium can occur with trifluridine cytotoxicity
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