Microbiology - Prions, Viroids, Viruses
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| Prions, Viroids, Viruses | missing link btwn non-living & living b/c don't have all characteristics of living; lack ability to reproduce on their own; are infectious agents & reproduce inside host cells; obligate intracellular parasite | ||||
| Prions | proteins, smallest disease agent; linked to Creutzfeld-Jakob Disease (mental degeneration), Kuru-Canabalism; Bovine Spongiferous Encephalitis (Mad Cow Disease); Scrapie (Sheep Disease) | ||||
| Prions | Creutzfeld-Jakob Disease | ||||
| Creutzfeld-Jakob Disease | Mental Degeneration | ||||
| Prions | Kuru | ||||
| Kuru | Cannibalism | ||||
| Prions | Bovine Spongiferous Encephalitis | ||||
| Bovine Spongiferous Encephalitis | Mad Cow Disease | ||||
| Prions | Scrapie | ||||
| Scrapie | Sheep Disease | ||||
| Prusiner | 1997 Nobel prize - Scrapie | ||||
| Viroid | made up of RNA; causes only plant diseases | ||||
| Viruses | made up of at least capside (protien) & 1 of 4 kinds of Nucleic Acid | ||||
| 4 kinds of Nucleic Acid | Double Stranded DNA & RNA, Single Stranded DNA &RNA | ||||
| Viruses | some contain envelope | ||||
| Viruses | Are genetic parasites | ||||
| Genetic parasites | Depend on host metabolism for reproduction | ||||
| Polio virus | only virus capable of reproduction w/o intact host cells | ||||
| Venter | 2003; synthesized 'A' phage (bacterial virus) | ||||
| Smallest Virus | Enteroviruses 30nm | ||||
| Largest virus | Orthopox 300nm | ||||
| Shape of Viruses | Helical, polyhedral - iscosa hedral, Complex - bullet shaped; Spherical - enveloped | ||||
| 1st virus to be indentified | Tobacco Mosaic Virus (TMV) | ||||
| TMV | filterable agent | ||||
| Beijerinck (1899) | characterized them as infectious | ||||
| Stanley (1935) | crystallized TMV; 1st observed virus TMV | ||||
| viral replication | lytic & lysogenic cycles in phages |
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Created by:
JYarger
on 2006-03-09
