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2 anti-infectives

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PENICILLIANS
BETA-LACTAMS
CEPHALOSPORINS
TETRACYCLINES
Gentamicin (Gramycin)
QUINOLONES (flouroquinolones)
Ciproflaxacin (Cipro)
amoxicillin (Amoxil), penicillin V potassium (Pen-Vee K)   (blank)   (blank)   (blank)   (blank)   (blank)   (blank)  
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amoxicillin (Amoxil), penicillin V potassium (Pen-Vee K)   4 sub-classes; 1. penicillians 2. cephalosporins 3. carbapenems,4. monobactams.   Cefazolin sodium (Andef, Kefzol, ceftriaxon (rocephin, cephalexin (Keflex)   Doxcycycline   aminoglycoside   cipro   flouroquinolones  
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gram + bacteria; staphlococcus   break down chemical bond between Carbon and Nitrogen   3 generations 1st - gram + coverage; 2nd gen- both; 3rd gen- gram - coverage 4th gen. cefapime   contraindicated in peds b/c of mild interaction   toxic to ears and kidney   very potent broad spectrum- kill bacterial by altering DNA gyrase   For the treatment of infections caused by susceptible gram-negative bacteria, including E. coli,  
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SE- uticaia, puritis & andioeduam   betalactamase- enzyme produced by bacteria strains that makes bacteria more resistant   (antibiotic structurally related to penicillins   SE-discloation of permananet teeth, hypoplasia in fetus and children; possible retard of skeltal dev, and photosensitivity   bind to ribosomes (30S) and prevent protien sythesis of bacteria   interact with antacids, iron & zink   CNS: Headache, dizziness, insomnia, fatigue, somnolence, depression, blurred vision CV: Arrhythmias, hypotension, angina EENT: Dry eye, eye pain, keratopathy GI: Nausea, vomiting, dry mouth, diarrhea, abdominal pain  
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most common adverse reaction- urticaria, pruritis angioedma   (blank)   3rd generation - cefoxitin & ceftazidime   coadminstration with milk, antacids, iron salts may decrease oral absoprtion of --CI preganant /lactating women and pediatric patients   tx of gram negative   (blank)   (blank)  
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Created by: mashechka
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