Antiinfectives
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each of the black spaces below before clicking
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Help!
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| What are the aerosolized antiinfectives we have learned about? | Pentamidine-Nebupent, Ribavirin-Virazole, Tobramycin-TOBI, Zanamivir-Relenza
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| What is the recommended dosage for Pentamidine/NebuPent? | 300mg/6ml sterile water; once/4wks
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| What is the recommended dosage for Ribavirin/Virazole? | 20mg/ml; 12-18hrs/day for 3-7days by SPAG
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| What is the recommended dosage for Tobramycin?TOBI? | 300mg bid; 28 days on/28 days off; >6yrs
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| What is the recommended dosage for Zanamivir/Relenza? | 10mg bid with DPI diskhaler; bid 5 days
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| What are the indications for Pentamidine/NebuPent? | PCP prophylaxis in HIV pt
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| What are the indications for Ribavirin/Virazole? | RSV
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| What are the indications for Tobramycin/TOBI? | P. aeruginosa in CF
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| What are the indications for Zanamivir/Relenza? | Influenza
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| What is the mode of action for Ribavirin/Virazole? | Inhibits DNA replication/reproduction
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| What special precautions should be taken when delivering Ribavirin/Virazole? | PPE's should always be worn; Women who are pregnant or planning pregnancy should not administer
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| What special precautions should be taken when administering Pentamidine/NebuPent? | Use Respigard II neb system, administer in negative pressure room or under exhaust, always wear PPEs
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| What is the mode of action for Pentamidine/Virazole? | Inhibits DNA, RNA, phospholipids and protein synthesis
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| What is the mode of action for Ribavirin/Virazole? | Stops viral DNA replication
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| What is the mode of action for Tobramycin/TOBI? | Bacterialcidal - blocks protein synthesis
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| What is the mode of action for Zanamivir/Relenza? | Binds to viral enzyme and block action
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| What are the side effects of Tobramycin/TOBI and Gentamicin? | Dizziness, nausea, neuromuscular blockade;
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| What can worsen the side effects of TOBI and Gentamicin? | Myasthenia and use of neuromuscular blockades
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