Indications, Mode of Action, Side Effects
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| Beta Agonists | Airway obstruction in asthmas and COPD
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| Albuterol, Levalbuterol, Metaproterenol | Acute airflow obstruction
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| Salmeterol, Formoterol, Arformetorol | Maintenance bronchodilation, control bronchospasm
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| Racemic Epi | Reduce AW swelling after extubation or epiglottitis, croup, or control AW bleeding
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| What is the mode of action of adrenergic drugs? | stimulation of Beta 2 receptors located in bronchial smooth muscle`
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| What are the effects of Alpha receptor stimulation? | Vasoconstriction in upper AW, decongestion
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| What are the effects of Beta 1 receptor stimulation? | Increased heart conductivity, heart rate, and contractile force
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| What are the effects of Beta 2 receptor stimulation? | Relaxation of bronchial smooth muscle, mucociliary clearance, some inhibition of inflammation
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| What are the side effects of Beta adrenergic bronchodilators? | Tachycardia, nervousness, tremors, nausea
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| Terbutaline | stop contractions in premature labor
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| What is responsible for the breakdown of Beta agonist? | COMT
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| What breaks down C3'5'AMP to 5 AMP? | Phosphodiesterase
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| How does bronchodilation occur? | Attachment to Beta 2 receptors - Gs protein - adenylyl cyclase - C3'5'AMP
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