respiratory pharm drugs
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| What are the antiinfective drugs? | Pentamidine isethionate (NebuPent), ribavirin (Virazole), tobramycin (TOBI) and zanamivir (Relenza)
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| What is Pentamidine indicated for? | the prevention of Pnuemocystis pneumonia (PCP) in high risk HIV infected patients
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| What is Ribavirin indciated for? | the treatment of hospitalizaed infants with severe lower respiratory tract infection caused by RSV
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| What is Tobramycin indciated for? | the management of chronic P. aeruginosa infection in cystic fibrosis.
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| Zanamivir is indciated for what? | the treatment of uncomplicated acute illness caused by the influenza virus
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| Why is aerosol administration used for pentamidine? | local traget delivery, with fewer side effects
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| How is pentamidine administrated? | the Respirgrad II nebulizer, 5-7 L/min
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| Mode of action for Pentamidine? | blocks RNA and DNA synthesis, inhibits oxidative phosphorylation and interfers with folate transformation. (unknown)
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| How can you prevent local airway reaction with pentamidine? | use a beta-adrenergic like ipratropium
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| Concerns with using pentamidine are what? | risk of infection with TB and exposure to the drug itself
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| What does RSV cause? | bronchiolitis and pnuemonia
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| What is RSV-IGIV? | respiratory syncytial virus immune globulin intravenous, a sterile liquid formulation of IgG containing neutralizing antibody to RSV
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| What is RSV-IGIV indicated for? | the preventionof serious lower respiratory tract infection with RSV
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| What does RSV-IGIV offer? | a prophylactic alternative to the treatment of acute RSV infection with aerosolized ribavirin
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| What is Palivizumab indciated for? | the prevention of serious lower respiratory treact disease caused by RSV
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| What is Cystic Fibrosis? | an inherited disease of the exocrine glands, affecting the pancreas, respiratory system and apocrine glands.
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| What is Respiratory Syncytial virus? | a virus that causes formation of syncytial masses in infected call structures
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| What is PCP? | Pneumocystis pneumonia, an interstitial plasm cell pneumonia caused by the oraganism pneumocystis carinii.
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