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Peds Asthma

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Question
Answer
What is asthma?   airway inflammation, airway hyperreactivity, (reversible) airway obstruction  
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Sx of Asthma   wheezing, coughing, chest tightness or pain, shortness of breath  
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Assessing frequency of sx:   number of hospitalizations/ICU admissions, Number of ER or PMD visits, Missed days of school or work, Days/week with sx  
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Asthma Triggers   URI's, exercise, changes in weather, exposure to irritants, emotional states, allergens, cold air, seasons, medications, food additives  
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when taking an asthma hx, use the term   respiratory sx (as opposed to just saying asthma sx)  
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PE of Asthma pt   pulmonary, HEENT (polyps, postnasal drip), skin (eczema), extremities (if clubbing likely not asthma)  
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nasal polyps and clubbing suggest   Cystic Fibrosis  
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Differential Diagnosis of chronic asthma   anatomic abnormality, infection, Foreign body, cystic fibrosis, gastroesophgeal reflux, bronchopulmonary dysplasia, pulmonary edema, laryngeal dysfunction  
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Most common trigger for Asthma   Infection  
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Lab Studies include: Blood tests - CBC + differential immune work up QIGs, antibody titers, Sweat test (only at a CF center), Skin testing, GER evaluation, and   Pulmonary function - spirometry + lung volumnes, methacholine challenge exercise testing, CXR and sinus films, bronchoscopy  
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Skin testing   does not tell you what you are allergic to, but what you are sensitive to. Sensitivity must be tied to allergies  
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CXR indications   Atypical presentation, asymmetric breath sounds, suspicion of FB, lack of clinical improvement, worsening clinical course, persistent oxygen requirement  
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CXR findings   nl, hyperinflation, peribronchial thickening, atelectasis versus infiltrate, pneumothorax/pneumomediastinum  
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test to assist in asthma diagnosis   methacholine challenge  
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Tx for asthma   patient education, prevention/environmental control, pharmacotherapy, home monitoring  
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Ideal asthma management tx   daily anti-inflammatory agent plus PRN bronchodilator agent  
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Bronchodilators   methylaxanithine derivatives, beta-2 agonists, anti-cholinergics  
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Anti-inflammatory agents   mast cell stabilizers, steroids, leukotriene inhibitors, anti-IgE antibodies  
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Salmeterol (Serevent) note:   it is a Long acting Beta Agonist (LABA) and should not be used as monotherapy  
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Cromolyn (intal) and nedocromil (tilade) are   mast cell stabilizers  
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Beclomethasone, triamcinolone, flunisolide, fluticasone, budesonide are   inhaled steroids. Wiped out by liver in the first pass, so don't stay in the system long to have systemic effects  
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Advair   Fluticasone and Salmeterol  
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Symbicort   Budesonide and formoterol  
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Combination therapy indication   NAEPP Guidelines: part of first line therapy for moderate to severe persistent asthma  
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LABA black box warning (serevent)   sudden death, higher rates in AA  
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Systemic steroids are used to treat:   acute asthma attacks. Duration of therapy: mild to mod flare: 3-5 days with no taper required, moderate to severe flare: 5 days with taper as per clinical course  
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Topical side effects of inhaled steroids   oral thrush, change in phonation. Systemic side effects: dose dependent, uncommon if total daily dose is <1200mg of beclomethasone/day  
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Short term side effects of systemic steroids   increased appetite, weight gain, fluid retention, irritability  
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Long term side effects of systemic steroids   growth suppression, adrenal suppression, immunosuppression, decreased bone density, htn, DM, glaucoma, cataracts  
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Assessing canister fullness   count the amount of medication used; some meds have counters on them  
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why don't you use an inhaler "bone dry"   drug is likely gone and patient is getting more propellant  
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Peak flow meter uses: monitor daily pulmonary fxn, measure diurnal variation in pulmonary fxn, monitor degree of airway obstruction, predict asthma exacerations before symptomatic, and   monitor response to asthma therapy, provocational testing (trigger assessment), assess if sx are due to asthma  
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Peak flow meters should be used _____   daily  
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Candidates for peak flow meters: all pts with severe asthma, select pts with moderate asthma, pts with poorly controlled asthma, and   pts unsure of their asthmatic triggers, pts who underestimate the degree of their illness and extent of their airway obstruction  
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Establishing peak flow zones   baselines values, personal best, percent predicted  
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>80% of peak flow   Green zone  
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50-80% peak flow   yellow zone  
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<50% peak flow   red zone  
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Poor asthma control may suggest   not enough meds, confounding feature being missed (allergies, GER, CF), wrong diagnosis, Suboptimal medication delivery (poor technique (no spacer), poor adherence  
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When to refer for asthma   acute life-threatening asthma attack, mod to severe asthma, steroid dependent asthma, atypical/complicated asthma, poor response to optimal tx, confounding variables are present, more complicated dx studies required  
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In a well-controlled asthmatic, albuterol should last   1 year. Don't do an auto refill  
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If pt has 2 or more exacerbations per week, they need an   inhaled steroid.  
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Patient education   make sure they understand the difference between inhaled steroid vs. albuterol (rescue medicine)  
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