| Question |
 |
|
| Answer |
|
|
| Epinephrine GENERIC NAME |
Epinephrine |
| Epinephrine BRAND NAME |
Adrenalin |
| Epinephrine CLASS |
Sympathomimetic |
| Epinephrine MECHANISM OF ACTION |
Increased BP, HR, and bronchodilates by binding with bothalpha and beta receptors |
| Epinephrine INDICATIONS |
Bronchospasms, Allergic and anaphylactic reactions, and Cardiac arrest. |
| Epinephrine CONTRAINDICATIONS |
Hypertension, hypothermia, pulmonary edema, myocardial ischemia, Hypovolemic shock. |
| Epinephrine ADVERSE REACTIONS |
Anxiety, nervousness, tremors, CP, arrhythmias, HTN, N/V, HA |
| Epinephrine NOTES ON ADMINISTRATION |
Pregnancy safety C. May increase myocardial oxygen demand. |
| Epinephrine INCOMPATABILITIES/DRUG INTERACTIONS |
Potentiates other sympathomimetics, deactivated by alkaline solutions (i.e. sodium bicarbonate) monamine oxidase inhibitors may potentiate effects. |
| Epinephrine DOSE/ROUTE, Adult, Mild allergic reactions and asthma |
0.3-0.5 mg of 1;1000 SC. |
| Epinephrine Dose/Route, Adult Anaphylaxis |
0.1mg of 1:10,000 iv/io over 5min. |
| Epinephrine Dose/Route, Ault Cardiac arrest IV/IO dose |
1 mg of 1;10,000 every 3-5 minutes during resuscitation. Follow each dose with 20 mL flush and elevate arm for 10-20 secs. |
| Epinephrine Dose/Route.Pediatric Mild allergic reactions and asthma |
0.01 mg/kg of 1;1,000 solution SC. |
| Epinephrine Dose/Route Pediatric Cardiac arrest |
IV/IO dose 0.01 mg/kg of 1;10,000 solution every 3-5 minutes during arrest. |
| Epinephrine ONSET OF ACTION |
Immediate. |
| Epinephrine PEAK EFFECTS |
Minutes. |
| Epinephrine DURATION OF ACTION |
Several minutes. |
| Epinephrine AZ DRUG BOX SUPPLY RANGE |
1:1,000 = 30 mg Multidose Vial.1:10,000 = 5 mg. |
| Neo-synephrine GENERIC NAME |
PHENYLEPHRINE NASAL SPRAY 0.5% |
| Neo-synephrine BRAND NAME |
Neo-synephrine Nasal Spray 0.5% |
| Neo-synephrine CLASS |
Topical vasoconstrictor |
| Neo-synephrine MECHANISM OF ACTION |
Stimulates a receptors in the blood vessels of the nasal mucosa which causes their constriction and thereby decreases the risk of nasal bleeding. |
| Neo-synephrine INDICATIONS |
Facilitation of nasotracheal intubation |
| Neo-synephrine CONTRAINDICATIONS |
Known allergy to medication |
| Neo-synephrine ADVERSE REACTIONS |
Hypertension, palpitations, Tremors |
| Neo-synephrine NOTES ON ADMINISTRATION |
none |
| Neo-synephrine INCOMPATABILITIES/DRUG INTERACTIONS |
none |
| Neo-synephrine DOSE/ROUTE,ADULTS |
2-4 sprays in each nostril before attempting tube insertion |
| Neo-synephrine DOSE/ROUTE Peds |
None |
| Neo-synephrine ONSET OF ACTION |
Seconds |
| Neo-synephrine PEAK EFFECTS |
30 minutes |
| Neo-synephrine DURATION OF ACTION |
30minutes to 4 hours |
| Neo-synephrine AZ DRUG BOX SUPPLY RANGE |
1 Bottle |
| Mag GENERIC NAME |
None |
| Mag BRAND NAME |
Magnesium Sulfate |
| Mag CLASS |
Electrolyte |
| Mag MECHANISM OF ACTION |
It controls seizures by blocking peripheral neuromuscular transmission, and is also a peripheral vasodilator and an inhibitor of platelet function. |
| Mag INDICATIONS |
Torsades De Points, arrhythmias associated with hypomagnesemia, Eclampsia, and prophylactically in preeclampsia, and Status Astmaticus |
| Mag CONTRAINDICATIONS |
Heart blocks, GI obstruction, renal impairment. |
| Mag ADVERSE REACTIONS |
facial flushing, diaphoresis, hypotension, hypothermia, weakness, muscle paralysis, and cardiac, cns, and respiratory depression |
| Mag NOTES ON ADMINISTRATION |
Pregnancy category B. Recommended that this drug not be given in the 2 hours before delivery, if possible. |
| Mag INCOMPATABILITIES/DRUG INTERACTIONS |
May enhance the effects of other CNS depressants |
| Mag DOSE/ROUTE Adult, Seizure activity associated with pregnancy |
1-4g IV/IO over 3 minutes. Maximum dose of 40g per day. |
| Mag DOSE/ROUTE Adult, Cardiac arrest due to hypomagnesemia or torsade de pointes |
1-2g diluted in 10ml of D5W IV/IO over 5-20 minutes. |
| Mag DOSE/ROUTE Adult, Torsade de pointes with a pulse or AMI with Hypomagnesemia |
Loading dose of 1-2g mixed in 50-100 ml in D5W over 5-60 minutes IVZ. |
| Mag DOSE/ROUTE Pediatric, IV/IO infusion |
25-50 mg/kg (max dose 2g) over 10-20 minutes. Faster for torsade de pointes. |
| Mag DOSE/ROUTE Pediatric, for asthma |
25-50mg/kg over 10-20 minutes. Max dose 2g |
| Mag ONSET OF ACTION |
IV/IO immediate. IM 3-4 hours. |
| Mag PEAK EFFECTS |
N/A |
| Mag DURATION OF ACTION |
30 minutes IV/IO, 3-4 hours |
| Mag IM AZ DRUG BOX SUPPLY RANGE |
5g. |
| Calcium Chloride GENERIC NAME |
none |
| Calcium Chloride BRAND NAME |
Calcium Chloride |
| Calcium Chloride CLASS |
Electrolyte |
| Calcium Chloride MECHANISM OF ACTION |
Increases cardiac contractile state (positive inotropic effect) |
| Calcium Chloride INDICATIONS |
1. Hypoglycemia 2. Hyperkalemia 3. Magnesium sulfate overdose 4. Calcium channel blocker overdose |
| Calcium Chloride CONTRAINDICATIONS |
1. Hypercalcemia 2. V-fib 3. Digitalis toxicity |
| Calcium Chloride ADVERSE REACTIONS |
1. Bradycardia, 2. Asystole. 3. Hypotension 4.Peripheral Vasodilation. 5. Local necrosis. 6. Nausea and Vomiting. |
| Calcium Chloride NOTES ON ADMINISTRATION |
Pregnancy safety C. |
| Calcium Chloride INCOMPATABILITIES/DRUG INTERACTIONS |
May worsen arrhythmias secondary to digitalis toxicity. May antagonize the effects of verapamil. |
| Calcium Chloride DOSE/ROUTE Adult |
500-1000mg (5-10 ml of a 10% solution) IV/IO May be repeated as needed. |
| Calcium Chloride DOSE/ROUTE Pediatric |
20mg/kg slow IV/IO push. Maximum 1 gram dose. May be repeated in 10 minutes. |
| Calcium Chloride ONSET OF ACTION |
3-5 minutes |
| Calcium Chloride PEAK EFFECTS |
5-15 minutes. |
| Calcium Chloride DURATION OF ACTION |
4 hours (dose dependent). |
| Calcium Chloride AZ DRUG BOX SUPPLY RANGE |
1 Gram |
| Adenosine GENERIC NAME |
Adenosine |
| Adenosine BRAND NAME |
Adenocard |
| Adenosine CLASS |
Endogenous nucleotide |
| Adenosine MECHANISM OF ACTION |
Slows conduction of the electrical impulses at the AV node |
| Adenosine INDICATIONS |
Stable reentry SVT |
| Adenosine CONTRAINDICATIONS |
Sick sinus syndrome, second or third degree heart block, Poison or drug induced tachycardia. |
| Adenosine ADVERSE REACTIONS |
Sense of impending doom, flushing, chest pressure, throat tightness, Numbness, may cause a brief episode of Asystole after administration |
| Adenosine NOTES ON ADMINISTRATION |
Pregnancy category C. Short half life |
| Adenosine INCOMPATABILITIES/DRUG INTERACTIONS |
May cause Bronchoconstriction in asthmatic patients, Tegretol may block the effects of adenosine. |
| Adenosine DOSE/ROUTEAdult |
6mg over 1-3 seconds followed by a 20ml saline flush. If no response after 1-2 minutes repeat with a dose of 12mg over 1-3 seconds. If no change repeat 12mg over 1-3 sec. Total dose 30mg. |
| Adenosine DOSE/ROUTE Peds. |
0.1-0.2 mg/kg rapid IV. Max single dose 12mg. |
| Adenosine ONSET OF ACTION |
seconds |
| Adenosine PEAK EFFECTS |
seconds |
| Adenosine DURATION OF ACTION |
12 seconds |
| Adenosine AZ DRUG BOX SUPPLY RANGE |
30mg |
Ch.18 LTI-MA 509
