Hematology Variations in WBCs Morphology
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| Cells showing a variations in morphology in an abnormal response to a stimulus are... | Pathological
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| Cells show variation in morphology but no physiological impairment results. | Non-Pathological
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| Cells show variation in morphology as a normal body response to invasion by a bacteria or virus. | Reactive
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| Neutrophils with more than 6 lobes are defined as | HYPERsegmented
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| Why do hypersegs form? | DNA production defect slows production down & the nucleus forms many lobes.
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| True or False Hypersegmented Neutrophilic cell size remains the same with hypersegmentation. | False. They can become larger than 15 microns
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| The cytoplasm of Hypersegmented neutrophils is less funtional. True or False | False. They cytoplasm is normal in appearance and is still phagocytic.
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| Barr bodies are significant only when? | In diseases of chromosomal abnormailities.
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| Disease conditions of hypersegmented neutrophils include | Megaloblastic anemias (Folic acid deficency, or pernicious anemia), cancer therapy, chronic infections.
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