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CM Dermatology Inflammatory Dermatoses

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Etiology of Psoriasis   A systemic,immunologic,genetic disease manifesting in skin and,or joints. Many of these people have arthritis. Usually comes on in teens, young adults  
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Most common locations to find psoriasis   Scalp (80%), elbows (78%), Legs (74%)  
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Psoriasis facts   usually symmetric, well-demarcated borders, scaly, raised lesions, pruritis is variable, pustules may outline lesions and occur palms and soles.  
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Psoriasis advice   soak in water to slough off, don't scrape off  
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Drugs that exacerbate psoriasis   lithium, beta-blockers, antimalarials, systemic steroids  
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Factors that flare psoriasis   Streptococcal infection, injury or trauma, Drugs, low humidity, emotional stress, overtreatment  
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Small papules of short duration (weeks to months), usually in children and young adults. DROP LIKE. 14-17% of psoriatic patients present initially and may follow a strep URI   Guttate Psoriasis  
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Red, scaly psoriasis all over is called   Erythrodermic Psoriasis  
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Sx and Signs of erythrodermic Psoriasis   Patients are ill: hypo-,hyperthermia,protein loss,dehydration, renal and cardiac failure  
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Superficial pustules is suggestive of   Pustular Psoriasis. Filled with neutrophils  
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Extracutaneous signs of Psoriasis   Nails: onycholysis,yellowish staining, pitting. Mucosa: geographic tongue. Joints: 10%-30% of psoriatic patients  
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Psoriasis joint swelling can also look like   RA, with ulnar deviation too.  
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Most common arthritis associated with psoriasis   asymmetrical arthritis. Other types: Symmetrical arthritis (like RA), distal interphalangeal joint dz, destructive polyarthritis, ankylosing spondylitis  
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Inflammatory cells involved in psoriasis   T-lymphocytes and cytokines  
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Psoriasis tx strategy   Initally control dz, decrease area involved, decrease erythema, scaling, and thickness. Use topical therapy, phototherapy, systemic therapy  
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Topical options   Anthralin, steroids, tars, vit d analogs, retinoids, taclonex ointment  
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dandruff is aka   seborrheic dermatitis. Can occur other places than the scalp  
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Pityrosporum ovale is a possible causative factor of   seborrheic dermatitis  
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Most common skin manifestation in AIDs patients   Seborrheic dermatitis; often precedes AIDs symptoms. Severity often parallels clinical deterioration  
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Best way to remove scales in seborrheic dermatitis   with fluid, gently  
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Seborrheic Dermatitis is associated with which neurologic disease?   Parkinson's  
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Persistent or resistant cases of seborrheic dermatitis should be cultured for   dermatophyte infection.  
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Tx for Seborrheic Dermatitis   frequent washing, topical steroids, shampoo (change type; pyrithione zinc, tar, sulfacetamide, ketoconazole, selenium).  
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Common,benign,usually asymptomatic,self-limited dermatoses. Evidence of viral origin. 20% of pts have recent hx of acute infection   Pityriasis rosea. muted red, and fine scale (much less than psoriasis), usually on trunk.  
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Collarette scale is associated with   Pityriasis rosea. Fine ring of scale within a plaque  
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Papular lesions in pityriasis rosea are found more commonly in   young children, pregnant women, and blacks. Lesions subside in 1-3 months  
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Pityriasis Rosea Therapy   most beneficial in the first week. antihistamines, topical steroids, oral prednisone, UVB phototherapy  
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If you see something that looks like Pityriasis rosea but is also on the hands and soles, get an   RPR to rule out syphillis  
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Lichen planus facts   Inflammatory cutaneous and mucosal reaction pattern of unknown originMean age of onset –males 40.3 and females 46.4. Eruption clears in one year in 68% of patients and recurs 49% of the time. Liver disease is a risk factor for LP.  
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______ is a post-bone marrow transplant graft-vs-host reaction   Lichen planus  
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Lacy reticulated pattern of white lines (wickham's stria) suggest   lichen planus  
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Common locations of lichen planus   flexor surfaces of wrists adn forearms, legs above the ankles. 20% of pts with lichen planus do not itch.  
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Common things in a ddx for red, scaly and papular lesions.   Psoriasis, Seborrheic dermatitis, Pityriasis rosea, Lichen Planus, 2ndary syphillis infection  
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