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Delerium and Dementia in the elderly

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Question
Answer
Impoverished thinking is associated with   Dementia. Delirium manifests more disorganized thinking  
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difficulty finding words (impoverished thinking) is associated with   Dimentia. Delirium is associated with incoherent, hesitant, slow or rapid speech  
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Dementia definition   chronic deterioration of mental function sufficiently severe to interfere wtih daily living. Key features: 1)gradually progressing coursre (usually months to years) 2) No disorder of alertness  
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Risk Factors for dementia   age, fam hx, genetic mutations (alzheimer's), head trauma, hormone replacement therapy, CVD risk factors (vascular dementia), Low education levels  
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Protective factors against dementia   lesiure activities, aerobic and strength training, educational attainment, reducing CVD risk factors, head trauma protection  
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Potentially reversible or arrestable conditions associated with dementia (very unlikely to be reversible!)   Hypothyroidism, Vitamin B12 Deficiency,Neurosyphyllis,Subdural Hematoma,Vascular diseases (Multi-infarct ,Binswanger’s),Space-occupying lesions,Normal pressure hydrocephalusDepression (“pseudodementia” or depressive pseudodementia)  
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Progressive degenerative diseases causing dementia   Alzheimer’s DiseaseDementia of the Lewy Body TypeParkinson’s Disease DementiaFrontotemporal Dementia (Pick’s Disease)Huntington’s DiseaseCreutzfeldt-Jakob DiseaseAIDS Dementia  
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No. 1 degenerative disease causing dementia   Alzheimers  
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25% of parkinson's patients will develop   dementia  
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Reversible Causes of Dementia Pneumonic   Drugs, Emotional disorders, Metabolic or endocrine disorders, Eye and ear dysfunctions, environmental, Nutritional deficiencies, Tumor and trauma, Infections, Atherosclerotic complications and alcohol  
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Drugs to be on the look out for with elderly and may be a reversible cause of dementia   Anticholinergics  
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Nutritional deficiencies that may be reversible causes of dementia   Vit B12, Folate  
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Symptoms tend to progress rapidly in: dementia or pseudodementia?   Pseudodementia and patient is very aware and bothered by the cognitive loss.  
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Near miss answers are uncommon in   depressed people (won't likely try).  
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Primary degenerative dementia (PDD)   another name for alzheimer's dz  
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CT and MRI in alzheimer's   not diagnostic  
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Brain biopsy in Alzheimer's shows   neurofibrillary tangles and neurtic plaques  
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Diagnosing Alzheimer's   this is a clinical diagnosis, and a diagnosis of exclusion. Multiple cognitive deficits manifested by memory impairment and at least 1 of the following: aphasia, apraxia, agnosia, disturbances in executive fxn. Impairment in social or occupational fxn  
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Alzheimer facts   generally presents in the 7th-8th decade, mean survival is 8-10 years  
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Mild Alzheimers   sx subtle and often undetected, decline of short-term memory  
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Moderate Alzheimers   Language abilities and ability to think abstractly and exercise judgement impairedDecline of visual and spatial skills  
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Severe Alzheimers   loss of long term memory, problem sleeping, weak unable to walk or talk, incontinent, completely dependent on the caregiver  
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Vascular dementia facts   M>F, >60, Stepwise time course of deficits, hx of htn, tia, stroke, focal neuro sx are common  
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Primary Degenerative Dementia Facts   F>M, >75, gradually progressive time course of deficits, hx of htn, stroke, tia, focal neuro sx are less common  
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Gait disturbance, incontinence and dementia is a triad seen in   normal pressure hydrocephalus  
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Main cause of Amnestic Syndromes   Thiamine deficiency, trauma or anoxia  
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Benign senescent forgetfulness   not really a dementia. person remembers what they forgot later.  
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Hx for the dementia patient   list drugs, cv and neuro hx, characterize sx (nature of the deficit, onset and RATE or progression, associated psych sx: depression, anxiety, agitation, paranoia, psychotic features), assess social situation, wandering, incontinence, endangering behavior  
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Assessing the social situation of the dementia patient   living arrangements, social supports, basic and instrumental ADLs  
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PE of the dementia patient   BP, CV exam, Neurologic, mental status exam: formal assessment is important, evaluate: memory, orienatation, intellectual fxn, judgment, affect, Folstein MMSE, clock drawing, fact test  
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Diagnostic studies in dementia pt   Blood studies: cbc, chem7, cal + phos, LFTs, Thyroid fxn, Vit B12 & folate, RPR (for latent syphilis) , ?ESR, ?HIV. Radiologic: CT or MRI, Other studies: neurophysiological testing  
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FACT test   Fruits, animals, colors and towns. Pt should be able to name at least 10 of each.  
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___ is a test for latent syphillis   Rapid plasma reagin (RPR)  
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Drug therapy for dementia   cholinesterase inhibitors (for mild to moderate: slows down decline by months, not a dramatic difference that can be seen immediately), NMDA antagonist (moderate to severe)  
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Delirium and prevention   Delirium is often preventable. Dementia is only rarely preventable.  
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