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Med. Chem. Spring Final 2005

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Drug Name
Chem Class
Pharm Class
MOA
Cocaine   Tropane derivative   Local anesthetic/CNS stimulant   Blocks Na channels/inhibits DA uptake  
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Benzocaine   Aminobenzoic ester   Local anesthetic   Blocks Na channels  
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Procaine   Aminobenzoic ester   Local anesthetic   Blocks Na channels  
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Tetracaine   Aminobenzoic ester   Local anesthetic   Blocks Na channels  
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Butamben   Aminobenzoic ester   Local anesthetic   Blocks Na channels  
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Propoxycaine   Aminobenzoic ester   Local anesthetic   Blocks Na channels  
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Chloroprocaine   Aminobenzoic ester   Local anesthetic   Blocks Na channels  
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Proparacaine   Aminobenzoic ester   Local anesthetic   Blocks Na channels  
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Dibucaine   Amide   Local anesthetic   Blocks Na channels  
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Bupivacaine   Amide   Local anesthetic   Blocks Na channels  
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Lidocaine   Amide   Local anesthetic   Blocks Na channels  
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Prilocaine   Amide   Local anesthetic   Blocks Na channels  
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Mepivacaine   Amide   Local anesthetic   Blocks Na channels  
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Etidocaine   Amide   Local anesthetic   Blocks Na channels  
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Ropivacaine   Amide   Local anesthetic   Blocks Na channels  
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Dyclonine   Amino ketone   Local anesthetic   Blocks Na channels  
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Pramoxine   Amino ether   Local anesthetic   Blocks Na channels  
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Fludrocortisone acetate   Steroid   Mineralocorticoid   Mediates Na/K exchange-inc. Na reabsorbtion  
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Cortisone   Steroid   Systemic glucocorticoid   Inhibits arachidonic acid release  
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Hydrocortisone   Steroid   Systemic glucocorticoid   Inhibits arachidonic acid release  
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Corticosterone   Steroid   Systemic glucocorticoid   Inhibits arachidonic acid release  
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Prednisone   Steroid   Systemic glucocorticoid   Inhibits arachidonic acid release  
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Betamethasone   Steroid   Systemic glucocorticoid   Inhibits arachidonic acid release  
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Dexamethasone   Steroid   Systemic glucocorticoid   Inhibits arachidonic acid release  
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Clobetasol propionate   Steroid   Topical glucocorticoid   Inhibits arachidonic acid release  
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Flucinolone acetonide   Steroid   Topical glucocorticoid   Inhibits arachidonic acid release  
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Fluticasone propionate   Steroid   Topical glucocorticoid   Inhibits arachidonic acid release  
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Triamcinolone acetonide   Steroid   Topical glucocorticoid   Inhibits arachidonic acid release  
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Testosterone   Steroid   Androgen   Testosterone agonist  
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Methyltestosterone   Steroid   Androgen   Testosterone agonist  
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Fluoxymesterone   Steroid   Androgen/anabolic   Testosterone agonist  
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Stanozolol   Steroid   Anabolic steroid   Testosterone agonist  
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Oxandrolone   Steroid   Anabolic steroid   Testosterone agonist  
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Nandrolone decanoate   Steroid   Anabolic steroid   Testosterone agonist  
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Finasteride   Steroid   Androgen hormone inhibitor   Inhibits 5a-reductase  
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Dutasteride   Steroid   Androgen hormone inhibitor   Inhibits 5a-reductase  
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Estradiol cypionate   Steroid   Estrogen   Estrogen agonsim  
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Estropipate   Steroid   Estrogen   Estrogen agonism  
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Ethinyl estradiol   Steroid   Estrogen   Estrogen agonism  
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Anastrozole   Triazole   Anti-estrogen   Reversibly inhibits aromatase  
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Letrozole   Triazole   Anti-estrogen   Reversibly inhibits aromatase  
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Exemestane   Steroid   Anti-estrogen   Irreversibly inhibits aromatase  
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Clomiphene   Stilbenediol   Anti-estrogen   Increases gonadotropin secretion  
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Tamoxifen   Stilbenediol   Anti-estrogen   Rev. estrogen receptor antag.  
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Toremifene   Stilbenediol   Anti-estrogen   Rev. estrogen receptor antag.  
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Raloxifene   Misc.   Anti-estrogen   Sel. estrogen receptor modulator  
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Norethindrone   Steroid   Progestin   Inhib. FSH/LH release  
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Norgestrel   Steroid   Progestin   Inhib. FSH/LH release  
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Levonorgestrel   Steroid   Progestin   Inhib. FSH/LH release  
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Desogestrel   Steroid   Progestin   Inhib. FSH/LS release  
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Progesterone   Steroid   Progestin   Progestin agonist  
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hydroxyprogesterone caproate   Steroid   Progestin   Progestin agonist  
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Medroxyprogesterone acetate   Steroid   Progestin   Progestin agonist  
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Megesterol acetate   Steroid   Progestin   Progestin agonist  
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Mifepristone   Steroid   Antiprogestin   Progestin antagonist  
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Tolbutamide   Sulfonylurea   Hypoglycemic   Stimulates insulin release  
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Tolazamide   Sulfonylurea   Hypoglycemic   Stimulates insulin release  
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Acetohexamide   Sulfonylurea   Hypoglycemic   Simulates insulin release  
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Chlorpropamide   Sulfonylurea   Hypoglycemic   Stimulates insulin release  
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Glyburide   Sulfonylurea   Hypoglycemic   Simulates insulin release  
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Glipizide   Sulfonylurea   Hypoglycemic   Stimulates insulin release  
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Glimepiride   Sulfonylurea   Hypoglycemic   Simulates insulin release  
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Metformin   Biguanide   Hypoglycemic   Increases glucose uptake  
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Acarbose   Carbohydrate   Hypoglycemic   Inhibits a-glucosidase  
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Miglitol   Carbohydrate   Hypoglycemic   Inhibits a-glucosidase  
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Rosiglitazone   Thiazolidinedione   Hypoglycemic   Activate PPAR  
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Pioglitazone   Thiazolidinedione   Hypoglycemic   Activate PPAR  
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Repaglinide   Misc.   Hypoglycemic   Stimulates insulin release  
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Nateglinide   Misc.   Hypoglycemic   Stimulates insulin release  
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Glucagon   Peptide   Glucose elevating agent   Simulates glycogenolysis  
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Diazoxideoral   Benzothiadiazine   Glucose elevating agent   Inhibits insulin release  
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Sulfadiazine   Sulfonamide   Antibacterial   Inhibits dihydropteroate synthase  
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Silver sulfadiazine   Sulfonamide   Antibacterial   Inhibits dihydropteroate synthase  
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Sulfasalazine   Sulfonamide   Antibacterial   Inhibits dihydropteroate synthase  
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Sulfisoxazole   Sulfonamide   Antibacterial   Inhibits dihydropteroate synthase  
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Sulfamethoxazole   Sulfonamide   Antibacterial   Inhibits dihydropteroate synthase  
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Trimethoprim   Pyrimidinediamine   Antibacterial   Inhibits dihydrofolate reductase  
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Nalidixic acid   Quinolone   Antibacterial   Inhibits DNA gyrase  
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Cinoxacin   Quinolone   Antibacterial   Inhibits DNA gyrase  
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Norfloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Ciprofloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Ofloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Lomefloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Enoxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Levofloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Sparfloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Gatifloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Moxifloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Trovafloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Alatrovafloxacin   Fluoroquinolone   Antibacterial   Inhibits DNA gyrase  
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Amantadine   Adamantane   Antiviral   Inhibits host cell penetration by virus  
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Rimantadine   Adamantane   Antiviral   Inhibits viral uncoating  
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Oseltamivir   Misc.   Antiviral   Inhibits neuraminidase  
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Zanamivir   Misc.   Antiviral   Inhibits neuraminidase  
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Ribavirin   Pryimidine nucleoside   Antiviral   Inhibits viral DNA polymerase  
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Amprenivir   Misc.   Antiviral   Protease inhibitor  
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Saquinavir   Misc.   Antiviral   Protease inhibitor  
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Indinavir   Misc.   Antiviral   Protease inhibitor  
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Ritonavir   Misc.   Antiviral   Protease inhibitor  
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Nelfinavir   Misc.   Antiviral   Protease inhibitor  
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Abacavir   Purine nucleoside   Antiviral   Comp. inhibits HIV-1 reverse transcriptase  
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Didanosine   Purine nucleoside   Antiviral   Comp. inhibits HIV-1 reverse transcriptase  
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Lamivudine   Pyrimidine nucleoside   Antiviral   Comp. inhibits HIV-1 reverse transcriptase  
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Stavudine   Pyrimidine nucleoside   Antiviral   Comp. inhibits HIV-1 reverse transcriptase  
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Zalcitabine   Pyrimidine nucleoside   Antiviral   Comp. inhibits HIV-1 reverse transcriptase  
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Zidovudine   Pyrimidine nucleoside   Antiviral   Comp. inhibits HIV-1 reverse transcriptase  
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Delavirdine   Misc.   Antiviral   Non-comp. inhibits HIV-1 reverse transcriptase  
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Efavirenz   Misc.   Antiviral   Non-comp. inhibits HIV-1 reverse transcriptase  
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Nevirapine   Misc.   Antiviral   Non-comp. inhibits HIV-1 reverse transcriptase  
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Acyclovir   Purine nucleoside   Antiviral   Inhibits viral DNA polymerase  
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Vidarabine   Purine nucleoside   Antiviral   Inhibits viral DNA polymerase  
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Famciclovir   Purine nucleoside   Antiviral   Inhibits viral DNA polymerase  
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Valacyclovir   Purine nucleoside   Antiviral   Inhibits viral DNA polymerase  
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Ganciclovir   Purine nucleoside   Antiviral   Inhibits viral DNA polymerase  
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Trifluridine   Pyrimidine nucleoside   Anitviral   Inhibits thymidylate synthetase  
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Foscarnet sodium   Phosphate   Antiviral   Inhibits viral DNA polymerase  
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