Stack 10211973
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| study or science of drugs | pharmacology
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| studies the absorption, distribution, metabolism and excretion of drugs | pharmocokinetics
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| enteral | mouth, NG, or rectal
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| parenteral | skin
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| percutaneous | topical, inhalation
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| solubility of a drug | absorption
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| how fast drugs can get to an area through the blood stream | distribution
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| biotransformation-the liver is chemically inactive | metabolism
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| elimination | excretion
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| is the length of time it takes to remove 50% of the drug being administered | half life
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| more severe reactions to drugs | adverse effects
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| damage to kidneys | nephrotoxicity
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| damage to the kidneys | hepatotoxicity
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| unique, not normal responses | idiosyncratic
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| unexpected reaction, reaction to drugs caused by antibodies | hypersensitivity; ex. penicillin
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| severe allergic reaction | anaphylaxis
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| Signs of hypersensitivity | hives, rash, itching and swelling
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| What happens when a person has a anaphylaxis reaction | heart stops, trouble breathing, and maybe be fatal
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| When one drug changes the action of another drug; | drug interactions
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| Where does metabolism take place | liver
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| when 2 drugs combined have the same effect as 1 active ingredient | additive effect
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| When one drug interferes with action of another drug | antagonistic
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| When one drug Q pushes drug B out of place at the receptor site - then drug A takes over giving only the effect from that drug. | displacement
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| when 2 drugs don't work together chemistry reaction - bad | incompatibility
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| when 1 drug promotes rapid excretion of another drug; therefor; increasing the effect | interference
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| effect of 2 drugs given at the smae time is greater than the effects of each drug given alone | synergistic effect
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| what is the route for topical ointment | percutaneous
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| where do you place a sublingual tablet | under the tongue
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| directly into dermis or subcutaneous or muscular, IV, IM | parenteral
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| Example of a sublingual tablet | nitrogylcerin
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| Where do you place a tablet that is buccal | against mucous membrane - cheek
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