Post Exam 2
Help!
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| Where are lipoproteins made? What is their job? | intestinal mucosa and liver. These proteins are found in the plasma and transport cholesterol and triglycerides to areas of utilization and storage
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| Definition of cholesterol? | Dietary lipid synthesized by the body
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| Def of triglyceride? | Dietary lipid used by body
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| What are the five types of lipoproteins? | Chylomicrons. VLDL. LDL. IDL. HDL.
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| What causes raised levels of lipoproteins? | Diets high in sat fat and cholesterol.
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| Explain chylomicron. | Large lipoprotein molecule created by absolrpion of lipids by the cells in the small intestine. They transport lipids to adipose tissue to be broken down by lipoprotein lipase.
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| Rank the 4 lipoproteins (skip IDL) from most triglyceride content to least. | Most triglyceride is in Chylomicrons > VLDL > LDL > HDL. Least triglyceride is in HDL. So chylomicrons are all fat no muscle (protein)
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| Rank the 4 lipoproteins (skip IDL) from most protein content to least. | HDL has most protein > LDL> VLDL > Chylomicron
So HDLs are all muscle (protein) and little fat.
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| Rank the 4 lipoproteins (skip IDL) from most cholesterol content to least. | LDL have a lot of cholesterol > HDL > chylomicron
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| Purpose of drug treatment | decrease in plaque formation and regression of existing plaque
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| 4 MOA of antihyperlipidemics | 1. decrease Lipoprotein production
2. Increase degradation
3. Increase cholesterol removal
4. Decrease absorption from other sources
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