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A&P.blood.labtest

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two components of whole blood   plasma and formed elements  
3 types of formed elements in whole blood   red blood cells, white blood cells & platelets  
red blood cells   carry oxygen & get rid of carbon dioxide  
white blood cells   fight infection  
platelets   are responsible for clotting  
hemotocrit   the percentage of total blood volume composed of red blood cells - diseases of the blood can be detected by measuring the red blood cell count  
normal hemotocrit   males - 40-54% while females have 38-47%  
normal red blood count   males: normal RBC 4.6-6.2 million RBC/cubic mm; for females, normal RBC is 4.2-5.4 million/cubic mm  
platelets normal count   250,000-400,000 platelets per microliter of blood  
WBC - white blood count   5,000-10,000 white blood cells /microliter of blood  
Differential white blood count   what is percentage of each of the five kinds of white blood cells?  
normal percentages WBC   neutrophils - 60-70%; lymphocytes, 20-30%; monocytes, 2-8%; eosinophils, 1-4%; and basophils, .5-1%  
what does WBC mean?   elevated neutrophil means bacterial infection; allergic reactions mean that eosniophil and basophil counts are elevated  
granular leukocytes (3 types)   basophils, easinophils, neutrophils  
2 types of agranular leukocytes   lymphocytes and monocytes  
neutrophil   WBC 2-4 lobes; purple color; phagocytized microorganisms  
basophil   stains blue-purple-looks as if it has no nucleus because the granules are so close together; releases histmine; promotes inflammation - basophils "fill" the body - also heparin; which prevents clot formation  
eosinophil   nucleus often bilobed, looks like neutrophil but its orange-red or bright red - the color - think "eo" orange or red - eleveated in parasitic infections  
monocyte no granules (agranulocyte   largest of blood cells - kidney-shaped or horseshoe-shaped nucleus - phagocytic cell  
lymphocyte - no granules (agranulocyte)   nucleus very round - takes ups entire cell - tumor control,  
platelet   cell fragment surrounded by plasma membrane - contains granules  
antigen   any substance that, when it comes in contact with other cells, induces a state of sensitivy or immune response Gr. "anti" -gen "producing"  
antigenic   having the properties of an antigen (allergen) - immunogenic  
antibody (Ab)   an immunoglobulin molecule with a aspecific amino acid sequence evoked in humans or other animals by an antigen and characterized by reacting specifically with the antigen in some demonstrable way,  
antigen   protein that can interact with an antibody  
antibody   looks like a letter "y" - specific to antigen  
agglutination   clumping - when antibodies in plasma bind to the antigens on the surfaces of red blood cells, they form molecular bridges taht connect red blood cells  
hemolysis   rupture of red blood cells; can be a reaction to blood transfusion  
antigen - also called agglutinogens   function and location - protein that can interact with an antibody - found on red blood cells  
antibodies or agglutinins   location and function - antibody that causes clumping or agglutination of the bacteria or other cells (red blood cells) - in plasma l. ad "to" gluten "clump"  
Rh- and Rh+ blood types   Rh+ means that person has certain antigens (the D antigens) on their RBC's red blood cells - about 85% of Caucasians & 88% African-Americans have this - a person with Rh- does NOT have these antigens  
Antigen/antibody reaction   when antibodies in plasma bind to antigens on red blood surface, they form molecular bridges that connect the red blood cells - this is called clumping or agglutination - can clotting within blood vessels, cause kidney damage, and even death. REactions c  


   


 

 

 

 

 

 
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