Renal System Physiology, Calculations
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| ECF | Increase in NaCL decrease K+
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| ICF | Decrease in NaCl Increase K+
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| plasma volume measured by | radiolableled albumin
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| ECV measured | inulin
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| Cx>GFR | net tubular secretion
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| Cx<GFR | net tubular reabsorption
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| Cx=GFR | there is no net secretion or reabsorption
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| PGE on afferent arterioles | dilate arterioles ↑ RPF, ↑GFR, so FF is constant
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| Angiotensin II on efferent arterioles | constriction ↑ GFR so ↑FF, ↓ RPF
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| Afferent arteriole constriction | ↓RPF ↓GFR NC in FF
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| Efferent arteriole constriction | ↑ GFR so ↑FF, ↓ RPF
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| ↑ plasma protein concentration | NC RPF ↓ GFR ↓FF
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| ↓ plasma protein concentration | NC RPF ↑ GFR ↑FF
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| constriction on ureter | NC RPF ↓ GFR ↓FF
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| what blocks efferent arterioles | ACE inhibitors
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| What blocks afferent arterioles | NSAIDS
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| clinical measure to estimate GFR | Creatinine clearance
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| which terminal vessels carry blood toward the glomerulus | Afferent arterioles
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| site reabsorption of all glucose and amino acids, and the majority of bicarbonate, sodium and water | PCT
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| site of active reabsorption K+, Na+, Cl- | Thick ALH`
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| site of 50% of urea absorption | PCT [passively]
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| Site of active reabsorption of Na+, Cl- | Early distal convoluted tubule
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| Site of action of thiazide diuretics | DCT
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| Site of action of K+ sparing diuretics | collecting tubules
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| section that is impermeable to water | thick ascending loop of henle
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| site where ammonia is excreted to act as a buffer for secreted H+ ions | PCT
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| Portion of the nephron which is impermeable to Na+ and passively reabsorbs water | Thin descending loop of Henle
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| Aldosterone sensitive site where Na+ is exchanged for K+ and H+ | collecting tubules
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| Site of active Ca2+ reabsorption that is controlled by PTH | early DCT
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| Site of action of loop diuretics | Thick ascending loop of Henle
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| Section where reabsorption of water is regulated by vasopressin | Collecting tubules
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| Site of action of carbonic anhydrase inhibitors | PCT
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| section which containes principle cells and intercalated cells | Collecting tubules
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| Site of 85% of all phosphate reabsorption [via cotransport] | PCT
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| RPF can be estimated | PAH
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| urine is more hypertonic | Thin descending loop of Henle
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| Makes urine more hypotonic | Early DCT, Thick Ascending Loop of henle
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| ANP action | [secrete atrial pressure]decrease Na+, increase GFR
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| PTH action | secreted in response to decrease plasma [Ca2+] increase Ca2+ reabsorption DCT decrease in PO reabsorption PCT
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| Aldosterone | secreted in response to decrease BV and increase plasma K+ causes Increase in Na+ reabsorption and K+ secretion
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| Vasopressin ADH | secreted in response to increase plasma osmolarity and decrease blood volume
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| AT II | increase intravascular volume --> in Na+ and HCO3- reabsorption
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Created by:
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