Anemia
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| macrocytic anemia | folate, B12 deficiency, pernicious anemia , megaloblastic | ||||
| pernicious anemia | lack of intrinsic factor | ||||
| normocytic, normochromic | acute blood loss, aplastic anemia - marrow fails to make three types of blood cells - anemia, neutropenia (decrease WBCs), and thrombocytopenia (decrease platelets); drugs that cause this are felbamate, chloramphenicol, phenytoin | ||||
| hypochromic, microcytic anemia | IDA, sickle cell, thalassemia | ||||
| anemia of renal failure | lack of EPO | ||||
| IDA labs lookl like... | decrease in ferritin, decrease in iron, decrease in Hgb, increase TIBC | ||||
| IDA symptoms | koilonmychias, angular stomatitis, glossitis, pica | ||||
| megaloblastic anemia looks like... | decrease in Hct, Hgb, decrease in RBC, increase in MCH | ||||
| What has neuropsychiatric symptoms? | B12 deficiency, not folate | ||||
| iron supplement PO per day | 200 elemental per day | ||||
| ferrous sulfate | 65 mg; feosol, fer-in-sol | ||||
| ferrous gluconate | 35 mg; fergon | ||||
| ferrous fumarate | 99 mg; femiron, feostat | ||||
| iron dextran | infed | ||||
| iron sucrose | venofer | ||||
| sodium ferric gluconate | ferlecitt | ||||
| iron counseling points | take on empty stomach, can take with OJ, can use OTC docusate if have constipation | ||||
| iron ADRs | dark colored stools, constipation, diarrhea, N/V | ||||
| recommended daily intake of Vitamin B12 | 2 mcg/day | ||||
| vegan should get this much B12 per day | 1000 mcg/day | ||||
| IM cyanocobalamine (B12) | 1000 mcg IM QD x 1 week, then 100-1000 mcg QW x 4 weeks; then 100-1000 mcg QM | ||||
| B12 ADRs | hyperuricemia, hypokalemia, sodium retention, cardiac problems, itching, diarrhea, anaphylaxis | ||||
| EPO ADRs | immunogencity : pure red cell aplasia, increase in BP | ||||
| Darbo ADRs | HTN, hypotension, edema, arrhythmia, N/V, diarrhea, constipation, fatigue, fever, HA, myalgia, arthralgia, limb pain, infection, dyspnea, cough |
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Created by:
cytoskeletor
on 2008-07-08