Anemia
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| macrocytic anemia | folate, B12 deficiency, pernicious anemia , megaloblastic
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| pernicious anemia | lack of intrinsic factor
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| normocytic, normochromic | acute blood loss, aplastic anemia - marrow fails to make three types of blood cells - anemia, neutropenia (decrease WBCs), and thrombocytopenia (decrease platelets); drugs that cause this are felbamate, chloramphenicol, phenytoin
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| hypochromic, microcytic anemia | IDA, sickle cell, thalassemia
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| anemia of renal failure | lack of EPO
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| IDA labs lookl like... | decrease in ferritin, decrease in iron, decrease in Hgb, increase TIBC
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| IDA symptoms | koilonmychias, angular stomatitis, glossitis, pica
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| megaloblastic anemia looks like... | decrease in Hct, Hgb, decrease in RBC, increase in MCH
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| What has neuropsychiatric symptoms? | B12 deficiency, not folate
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| iron supplement PO per day | 200 elemental per day
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| ferrous sulfate | 65 mg; feosol, fer-in-sol
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| ferrous gluconate | 35 mg; fergon
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| ferrous fumarate | 99 mg; femiron, feostat
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| iron dextran | infed
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| iron sucrose | venofer
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| sodium ferric gluconate | ferlecitt
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| iron counseling points | take on empty stomach, can take with OJ, can use OTC docusate if have constipation
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| iron ADRs | dark colored stools, constipation, diarrhea, N/V
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| recommended daily intake of Vitamin B12 | 2 mcg/day
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| vegan should get this much B12 per day | 1000 mcg/day
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| IM cyanocobalamine (B12) | 1000 mcg IM QD x 1 week, then 100-1000 mcg QW x 4 weeks; then 100-1000 mcg QM
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| B12 ADRs | hyperuricemia, hypokalemia, sodium retention, cardiac problems, itching, diarrhea, anaphylaxis
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| EPO ADRs | immunogencity : pure red cell aplasia, increase in BP
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| Darbo ADRs | HTN, hypotension, edema, arrhythmia, N/V, diarrhea, constipation, fatigue, fever, HA, myalgia, arthralgia, limb pain, infection, dyspnea, cough
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