First Aid neuro pharm

Quiz yourself by guessing what should be in each of the black rectangles below before clicking on it to display the answer.
        Help  

description
drug
agonist at opiod receptors to modulate synaptic transmission   opiod analgesics  
block Na+ channel; inhibit glutamate release   phenytoin  
increase DURATION of Cl- channel opening --> increase GABA(A) action   barbituates  
increase FREQUENCY of Cl- channel openeing --> increase GABA(A) action   BZD  
used for pain, cough suppression, diarrhea, acute pulmonary edema   opiods  
induction of anesthesia   barbituates (thiopental)  
for detox, especially EtOH withdrawl (DT), night terrors, sleepwalking   BZD  
neuro drugs that incrase P450   barbituates, phenytoin, carbamazepine  
SE: respiratory depression, pinpoint pupils, CNS depression   opioids  
additive CNS depression effects with EtOH   barbituates, BZD  
SE: nystagmus, diplopia, SLE-syndrome, increases P450   phenytoin  
BZD OD treatment   flumazenil --> competitive antag at GABA receptor  
opiod OD treatment   naloxone/naltrexone --> opioid receptor antag  
anti-seizure drugs also used for bipolar treatment   carbamazepine, lamotrigine, valproic acid  
1st line for tonic-clonic seizures   phenytoin, carbamazpine, valproic acid  
1st line for absence seizures   ethosuximide  
1st line for status epilepticus seizures   BZD (diazepam, lorazepam)  
1st line for status epilepticus prophylaxis   phenytoin  
1st line for trigeminal neuralgia   carbamazepine  
also used for peripheral neuropathy   gabapentin  
1st line for epilepsy in pregnancy and children   phenobarbital  
also used for myoclonic seizures   valproic acid  
also used for eclampsia seizures   BZD  
1st line to prevent eclampsia seizures   MgSO4  
increase Na+ channel inactivation   phenytoin, carbamazepine, valproic acid  
blocks voltage gated Na+ channels   lamotrigine  
increase GABA release   gabapentin  
increase GABA(A) action   phenobarbital, BZD  
increase [GABA]   valproic acid  
blocks thalamic T-type Ca++ channels   ethosuxamide  
drugs a/w Steven Johnson syndrome   ethosuxamide, lamotrigine, phenytoin, phenobarbital  
causes NTD; contraindicated in pregnancy   valproic acid  
inhaled anesthetic with hepatotoxicity   halothane  
most common drugs for endoscopy   midazolam (BZD)  
stimulates heart, increases cerebral blood flow, for kids < 13 y/o   ketamine  
depolarizing neuromuscular blocking drug   succinylcholine  
non-depolarzing neuromuscular blocking drug --> competes with ACh   tubocurarine, atracurium, mivacurium, pancuronum, vecuronium, rocuronium  
prevents Ca++ release from sarcoplasmic reticulum   dantrolene  
used to treat malignant hyperthermia, neuroleptic malignant syndrome   dantrolene  
Parkinson drugs   bromocriptine, amantidine, L-dopa/carbidopa, selegiline, benztropine  
DA agonist for Parkinson's   bromocriptine  
Parkinson's drug that increases DA release   amantidine  
Parkinson's drug that decreses ACh activity   benztropine  
CANNOT cross BBB   dopamine  
able to cross BBB   L-dopa  
given with L-dopa to increase bioavailability of L-dopa in brean and decrease peripheral effects   carbidopa  
inhibit MAO-B ---> prevents DA breakdown in brain   selegiline  
5HT(1D) agonist --> causes vasoconstriction   sumatriptan  
used for acute migraines, cluster headaches   sumatriptan  


   

 
 

 
 

 

 

 
www.eapps.com




Copyright ©2001-2009 John Weidner All rights reserved.
About -  Terms of Service -  Privacy Statement