B. Busey ANS Receptors
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| Receptor Type |  |
|
| Location | |
|
| Action | |
|
| M1- Cholinergic | CNS | IP3DAG Increase Calcium |
| M2- Cholinergic | Heart | Increase cAMP, Potassium |
| M3-Cholinergic | Smooth Muscle, Glands, Circular Iris | IP3DAG, Allow Drainage from Schlemm, Constrict Pupil, Accomodation, Increase GI motility/Secretions |
| Alpha1- Adrenergic | Postsynaptic- smooth muscle | IP3DAG, Vasoconstrict, Sphincter Constrict, Relax Detrusor, Dilate Pupil |
| Alpha2- Adrenergic | PreSynaptic- Smooth Muscle, Fat, Platelets, Nerve Terminal | Decrease cAMP |
| Beta1- Adrenergic | Heart | Increase cAMP, Increase HR and Contractions |
| Beta2- Adrenergic | Smooth Muscle/Cardiac Vessels, GI, Urinary | Increase cAMP, Eye Dilator, Relax Detrusor, Relax GI |
| Beta3- Adrenergic | Fat | Increase cAMP |
| D1 | Renal | Increase cAMP |
| D2-4 | CNS | Decrease cAMP |
|
