Stack #108798
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| an eye that does nto blink can accommodate a maximum of about __uL of liquid and ___after it blinks | 30, 10
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| a single drop of opthalmic solution is about | 50ul that is based on 20 drops/ml so much of the dose is lost but this is common occurance
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| extend corneal contact time by the use of viscosity and thickening agents are nice because they | decrease frequency of dosing, increase the ocular retention time, and increase the bioavailibility
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| the preparation of solutions ans suspensions for ophthalmic use requires special consideration with regard to | sterility, preservation, isotonicity, buffereing, viscosity, ocular bioavailablity, and packagin
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| the prefered method to sterilize ophthalmics is _____ at 121 degrees for 15 mins | autoclaving
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| if thermal instability is a factor an alternative such as ___ may be used | bacterial filters
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| two perservative used in multi use vials in opth are | benzalkonium chloride and benzathonium chloride
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| body fluids have osmotic pressure corresponding to that of a ___solution of sodium chloride | 0.9%
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| hypertonic solution added to the eye will do what with water | tendency to draw water from eye towards the solution in an effort to dilute and estblisha concetration equilibrium
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| a hypotonic solutions placed into the eye will | draw water from site of an ophthalmic application through the tissue of the eye
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| an E value is the amount of NaCl which has the same osmotic affect as | one gram of the drug. put another way if evalue was 0.12 the drug is 12% as effective as an equal weight of sodium chloride in contributing to tonicity
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