Rheumatic Diseases-15
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| Anemia | decrease in the number of red blood cells (RBD) or less than the normal quantity of hemoglobin in the blood.
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| Ankylosis | the fusion of a joint, often in an abnormal position, usually resulting from destruction of articular cartilage and subchondral bone, as occurs in rheumatoid arthritis.
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| Antibodies | a specialized immune protein produced because of the introduction of an antigen into the body. The production of antibodies is a major function of the immune system.
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| Apophyseal | refers to the articulations between the articular facets of adjacent vertebrae, or facet joints. These joints are frequent site of degenerative joint disease, or osteoarthritis, spondylitic and traumatic diseases.
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| Arthritis | inflammation or infection of a joint.
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| Boutonniere deformity | a common hand deformity secondary to the pathologic effects of RA resulting in a combination of PIP joint flexion and DIP joint hyperextension.
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| Bursitis | inflammation of the fluid-filled sac (bursa)that lies between a tendon and skin, or between a tendon and bone.
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| Carpal tunnel syndrome | resulting from compression on the volar aspect of the wrist, which then impinge upon the median nerve. This causes paresthesia of the palmar aspect of the thumb, the second and third digits, and the radial aspect of the fourth digit.
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| De Quervain’s tenosynovitis | hand deformity which involves extensors at the thumb, causing severe pain & discomfort, resulting in a decrease in hand function & the ability to grip
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| Diarthroses | are the most mobile joints and are by far the most common articular pattern. Because these joints possess a synovial membrane and contain synovial fluid, these joints are more commonly referred to as synovial joints.
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| Epstein-Barr virus (EBV) | virus causing infection, characterized by fatigue & general malaise. Infection w/EBV is fairly common & is usually a transient & minor thing. However, in some individuals EBV can trigger chronic illness. dangerous to people w/compromised immune systems.
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| Inflammation | int. response of the body to harmful stimuli; achieved by the increased move't of plasma & leukocytes from the blood into the injured tissues; biochemical events propagates & matures the inflammatory response, involving the local vascular & immune system.
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| Juvenile rheumatoid arthritis (JRA) | The most common rheumatic disease in childhood. The diagnostic criteria for JRA are onset at age younger than 16 years, persistent arthritis in one or more joints for at least 6 weeks, and exclusion of other types of childhood arthritis.
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| Osteoarthritis (OA) | also referred to as degenerative joint disease, is a noninflammatory joint disease that results in deterioration of articular cartilage and the formation of new bone or osteophytes on the joint surface.
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| Pannus | activation of the synovial cells which accumulate & create pannus, a malignant mass over the cartilage, leading to cartilage breakdown. Granulation tissue cont' to spread, the joint space is slowly effaced by fibrous adhesions & fibrous ankylosis paperers
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| Rheumatoid arthritis (RA) | arthritis refers to joint inflammation; “rheum” in rheumatoid refers to the stiffness, general aching, weakness, and fatigue that is experienced throughout the body.
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| Rheumatoid factor (RF) | antibody that's measurable in blood. Antibodies are normal proteins in our blood that are important parts of our immune system; however, RF is an antibody that's not usually present in the norm. individual. Prognosis for those with RF + factor............
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| Rheumatologist | A physician who specializes in treatment of rheumatic diseases.
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| Sjogren’s syndrome | is a chronic disease of unknown etiology causing corneal and conjunctival lesions and is characterized by dry eyes and mouth.
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| Swan-neck deformities | a deformity which results from contractures of the interosseus & flexor muscles & tendons, which in turn produce a flexor contracture of the MCP joint, compensatory hyperextension of the PIP joint, & flexion the DIP joint; common w/RA
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| Synovial | pertaining to, consisting of, or secreting synovia, the lubricating fluid of the joints, bursae, and tendon sheaths.
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| Tenosynovitis | inflammation of the synovial lining of the tendon sheath.
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