Antibody-Mediated Immunity
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| What is the definition of Antibody-Mediated Immunity? |
the production of specific Antibodies in response to invading microbes |
| What is the 1st step in Antibody-Mediated Immunity? |
ARRIVAL of microbes in Lymph Organ |
| What is the 2nd step in Antibody-Mediated Immunity? |
BINDING of Microbial Antigen to receptors on specific B-cells |
| What is the 3rd step in Antibody-Mediated Immunity? |
MITOSIS of a specific B-cell population (clone), programed to produce Opposing Antibodies |
| What is the 4th step in Antibody-Mediated Immunity? |
"activated" B-cells are TRANSFORMED into Plasma or Memory cells |
| What is the function of Plasma Cells? |
SYNTHESIZE IgM Antibodies 1st, then IgG in 2nd response |
| What is the function of Memory Cells? |
remain dormant for years, then quickly divide and become Plasma cells during a 2nd response |
| What is the significance of Memory cells? |
save time/life in case of 2nd arrival of microbes |
| Why do Microbes invade Lymph organs instead of Blood? |
1. Lower pressure; 2. Lymph organs are designed to pick up Microbes |
| When is Antibody-Mediated Immunity activated? |
after Non-specific Defense is breached |
| How long does it take for Antibodies to be produced during a 1st exposure? |
about 28 days |
| How long does it take for Antibodies to be produced during a 2nd exposure? |
about 7 days |
| What is the 5th step in Antibody-Mediated Immunity? |
Antibodies ATTACH to foreign cells Antigens and "mark" the cells for Phagocytosis by NK-cells or Macrophages |
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