| Question |
Answer |
| What is kidneys roll in blood pressure? |
Increased bp -> increased diuresis and natriuresis -> Decreased BV |
| What is pressure diuresis/natriuresis? |
A few mm hg increase -> doubles the effect of renal output. |
| What is the two primary determinants of the long-term arterial pressure level? |
Shifting the equilibrium point. That is to change the intake/outtake level in ren. |
| Decribe the arterial pressure in kidney. |
CO and peripheral resistant changes while arterial pressure in ren is constant. |
| Define hyper tension. |
Blood pressure s>135 d>90 |
| Hypertension causes? |
1) heart failure and coronary heart disease 2)increased bp-> cerbral infarkt (stroke) 3) increased bp-> hemorrage in ren |
| Hypertension is caused by? |
Excessive accumulation of extracellular fluid in the body. |
| Describe changes in circulary function during volume-loading hypertension! |
1) increased extracellular fluid volume-> increased blood volume -> increased CO -> increased bp actives baroreceptors-> Vasodilatation -> decreased resistance |
| Why does kidney failure cause high pressure? |
Kidney can't secrete salt -> hypertension |
| Salt causes? |
1) Stimulation of thirst center in medulla. |
| What is the salts effect on renin-angiotensin system? |
Increased salt intake->Increased ECV-> Increased BP-> Decreased renin & angiotensin-> decreased retention of salt and water-> Return of ECV back to normal-> normal BP |
| Why does aldesteronism lead to hypertension? |
Tumor or patological disorder in adrenal gland -> increase alderone release-> increased salt&water absorbtion ->hypertension |
| Describe the renin-angiotensin system! |
dec. bp->prerenin (stored in juxta glomeruler cells) ->renin (func. enzym) -> angiotensin-I (have a little vasoconstrion effect)-> angiotensin-II (lungs) |
| What does angiotensin-II (prod. lungs) have for effect? |
1)Vasoconstricter (arteriols and little on veins) 2)retention of water & salt (because of renvasoconstrion and better absorbtion) 3) release of aldorone (causes better absorbtion in ren) |
