| Question |
Answer |
| What bacteria looks like Chinese letters |
Corynebacter |
| What are the 5 bacteria causing Heart Block |
"Lyme Disease Salmonella typhii (typhoid) Chagas Disease (Whipple’s) Legionella Diptheria |
| What bacteria cause Reiter’s Syndrome |
Shigella IBD Crohn’s Chlamydia Yersina Reiter & Crohn Saw Yersina and got Chlamyia |
| What are the Low Complement bugs causing Cryoglobuniemia |
Influenzae Adenovirus Mycoplasma Hepatitis C EBV I AM HE |
| What are the drugs induced SLE |
Hydralazine INH Phenytoin Procainamide Penicillamine Ethosuximide H I PPPE |
| What are the drugs that Blast the BM |
"AZT Benzene Chloramphenicol Vinblastine Vinblastine Anilate Bone Cells |
| What are the Comma Shaped bugs |
"Vibrio Campylobacter Listeria H. pylori |
| What is the cresent shaped protozoa |
Giardia lamblia |
| What bacteria looks like Chinese letters |
Corynebacter |
| What are the TB Rx |
Rifampin INH Pyrazinamide Ethambutanol Streptomycin |
| What are the 6 Low Complement assocs. with Nephrotic Syndrome |
Serum Sickness PSGN SLE SBE Cryoglobinemia MPGN II |
| What drugs Induce p450 |
Barbiturates Alcohol Griseofulvin Carbamazapin Rifampine Quinidine Tetracycline Sulfa drugs |
| What drugs Inhibit p450 |
INH Dapsone Spirolactones Macrolides Amiodarone Cimetidine Ketoconazole Quinilones |
| What drugs are P450 Dependent |
Warfarin Estrogen Phenytoin Theophylline Digoxin |
| What disease is a Neutophil Deficiency |
Chronic Granulomatous disease CGD |
| What is another name for CGD |
NADPH Oxidase deficiency |
| What are the Side effects of Statins |
Myositis Hepatitis Increased liver enzymes |
| What are the painful genital Lesions |
Chancroid Herpes Lymphogranuloma inguinale |
| What is the painful chancroid lesion due to |
Hemophilus ducreyi |
| What are the 4 hormones with disulfide bonds |
Prolactin Insulin GH Inhibin |
| What are the Hookworms |
Necatur americanis Enterobius vermicularis Ankylostoma duodenale Trichuris trichurium Ascaris lumbercoides Strongyloides Hooks AS NEAT |
| What are the X-Linked enzyme Deficiencies |
G6-PD CGD Pyruvate dehydrogenase Def. Fabry’s Hunter’s Lesch-nyhan |
| HLA-DR2 |
Narcolepsy, Allergy, Goodpasture’s, MS |
| HLA-DR3 |
DM, Chronic Active Hepatitis, Sjogren’s, SLE, Celiac Sprue |
| What are the actions of Steroids |
Kills helper T-cells & eosinophils Inhibits Macrophage migration Inhibits Mast cell degranulation Inhibits Phospholipase A Stimulates protein synthesis Stablizes endothelium |
| What are the causes of Monocytosis |
Salmonella (typhoid) TB EBV Listeria Syphillis |
| E. Coli is the most common cause of what |
UTI Spontaneous bacterial peritonitis Abdominal abscess Cholecystitis Ascending cholangitis Appendicitis |
| What are the “Big Mama” anaerobes |
Strep bovis Clostridium melanogosepticus Bacteriodes fragilis |
| What are the “Big Mama” Rx |
Clindamycin Metranidazole Cefoxitin |
| What “big mama” bugs are associated with colon cancer |
Strep. Bovis Clostridium melanogosepticus |
| What are psammoma bodies |
Calcified CA’s |
| In what diseases are Psammoa Bodies present |
Papillary carcinoma of the Thyroid Serous cystadenocarcinoma of the ovary Meningioma Mesothelioma |
| What types of stones are formed from Proteus |
Struvite (90%) |
| What type of motility do Proteus have |
swarming |
| What are 5 indications of Surgery |
Intractable pain Hemorrhage (massive) Obstruction (from scarring) Perforation |
| What drugs cause Cardiac Fibrosis |
Adriamycin (Doxyrubicin) Phen-fen |
| What drug is used to tx cardiac fibrosis |
Dozaroxsin |
| What is the MCC of any ….penia |
"#1 = Virus #2 = Drugs |
| What is seen in the Salmonella Triad |
High Fever Rose spots (rash) Intestinal fire |
| What drugs cause Myositis |
Rifampin INH Predinsone Statins |
| What are the causes of Eosinophilla |
Neoplasms Allergies/Asthma Addison’s Dz Collagen Vascular Dz Parasites |
| What are the Killed Vaccines |
SIR Hep A |
| What are the IgA Nephropathies |
Henoch-Schoenlein P. (HSP) Alport’s Berger’s |
| What are the Drugs that cause Autoimmune hemolytic anemia |
PCN α-methyldopa Cephalosporins Sulfa PTU Anti-malarials Dapsone |
| What are the drugs that cause Autoimmune thrombocytopenia |
ASA Heparin Quinidine |
| What is the first MI enzyme to appear |
Troponin I |
| What is the 2nd MI enzyme to appear |
CK-MB |
| What is the 3rd MI enzyme to appear |
LDH |
| What bacteria have Silver Stains |
Legionella Pneumocysitis carinii H. pylori Bartonella henseslae (lymph node) Candida (yeast) |
| What drugs inhibit dihydrofolate reductase |
Trimethoprim/Sulfamethoxazole "Pyremethamin/Sulfadiazine |
| What drugs cause Pulmonary Fibrosis |
Bleomycin Bulsufan Amiodarone Tocainide |
| What are the macrophage deficiency diseases |
Chediak-Higashi NADPH-oxidase deficiency |
| What are the 7 Rashes of the Palms & Soles |
TSS Rocky Mountain Spotted Fever Coxsackie A (Hand/Foot & mouth dz) Kawasaki Syphillis Scarlet Fever Staph Scalded Skin Syndrome |
| What is the clue for cAMP |
Sympathetic CRH (cortisol) Catabolic |
| What is the clue for cGMP |
Parasympathetic Anabolic |
| What are the clues for IP3/DAG |
"Neurotransmitter GHRH All hypothalamic hormones xc cortisol |
| What is the clue for Ca+ |
Used by Gastrin only |
| What is the clue for Ca:Calmodulin |
Used by smooth muscle for contraction by distention |
| What is the clue for Tyrosine Kinase |
"Used by Insulins |
| What are the T & B cell deficiencies |
"WAS SCID CVID HIV HTLV-1 |
| What are the CLUES for WAS |
Thrombocytopenia IL-4 Infection Eczema Decrease IgM |
| What are the CLUES for SCID |
Framshift/Nonsense mutation Adenosine deaminase deficiency T-cell>B-cell Bacterial infections Fungal infections |
| What are the CLUES for CVID |
"Late onset Frameshift/Missense mutation Tyrosine Kinase deficiency |
| What are the inhibitors of Complex 1 of the ETC |
Amytal Rotenone |
| What are the inhibitors of Complex 2 of the ETC |
Malonate |
| What are the inhibitors of Complex 3 of the ETC |
Antimycin D |
| What are the inhibitors of Complex 4 of the ETC |
CN- CO Chloramphenicol |
| What are the inhibitors of Complex 5 of the ETC |
Oligomycin |
| What are the ETC chemical uncouplers |
DNP Free Fatty acids Aspirin |
| What type of uncoupler is Aspirin |
Physical uncoupler |
| What are the 4 sources of Renal Acid |
Urea cycle Plasma Collecting ducts Glutaminase |
| What are the 2 enzymes needed to make glycogen |
"Glycogen synthase Branching enzyme |
| What are the branching enzymes |
"Glycogen alpha-1,4 glycosyl transferase Glycogen alpha-1,6 glycosyl transferase |
| What is the rate limiting enzyme in the break down of glycogen |
Phosphorylase (Pi) |
| What type of acidosis do you see with obstructive pulmonary dz |
Respiratory acidosis |
| What Autoimmune Disease has the following Anti-smith Anti cardiolipin Anti-ds DNA Antibodies |
SLE |
| What Autoimmune Disease has the following Anti – histone Antibodies |
Drug induced SLE |
| What Autoimmune Disease has the following Anti-topoisomerase Antibodies |
PSS (Progressive Systemic Sclerosis) |
| What Autoimmune Disease has the following Anti-centromere Antibodies |
CREST |
| What Autoimmune Disease has the following Anti-GBM Antibodies |
Goodpasture’s |
| What does Goodpastures have antibody to |
Type IV collagen |
| What Autoimmune Disease has the following Anti-mitochondria Antibodies |
Primary biliary cirrhosis |
| What Autoimmune Disease has the following Anti-hair follicle Antibodies |
Alopecia areata |
| What Autoimmune Disease has the following Anti-IgG Antibodies |
Rheumatoid arthritis |
| What Autoimmune Disease has the following Anti-myelin receptors Antibodies |
MS |
| What Autoimmune Disease has the following Anti-ACh receptor Antibodies |
MG |
| What Autoimmune Disease has the following Anti-ribonuclear protein Antibodies |
Mixed Connective Tissue dz (MCTD) |
| What does Pernicious Anemia have antibody to |
Intrinsic factor |
| What Autoimmune Disease has the following Anti-epidermal anchoring protein receptors Antibodies |
Pemphigus vulgaris |
| What Autoimmune Disease has the following Anti-epidermal basement membrane protein Antibodies |
Bullous pemphigoid |
| What do you see with bullous pemphigoid |
IgG sub-epidermal blisters Oral blisters |
| HLA-DR2 |
Narcolepsy, Allergy, Goodpasture’s, MS |
| HLA-DR3 |
DM, Chronic Active Hepatitis, Sjogren’s, SLE, Celiac Sprue |
| HLA-DR3 & 4 |
IDDM(Type I) |
| HLA-DR4 |
Rheumatoid Arthritis, Pemphigus Vulgaris |
| HLA-DR5 |
JRA, Pernicious Anemia |
| HLA-DR7 |
Nephrotic Syndrome(Steroid induced) HLA-DR 3 & B8 |
| HLA-A3 |
Hemochromatosis(chromo. 6, point mut.-cysteine>tyrosine) |
| HLA-B8 |
MG |
| HLA-B13 |
Psoriasis |
| HLA-B27 |
Psoriais(only if w/arthritis) Ankylosing Spondylitis, IBD, Reiter’s, Postgonococcal Arthritis |
| HLA-BW 47 |
21 alpha Hydroxylas def.(Vit.D) |
| HLA-DR 3 & B8 |
Celiac Disease |