Hematology RBC
| Description: | Hema. RBC Morphology |
| Category: | Laboratory Science |
| Created by: | Ladybug9537 on 2009-05-08 |
| Question | Answer |
| Why is morphology of red cells important | Aids physicians in diagnosis and relates to the quality of the indices results. |
| A slide that is too thin | cobblestone effect and has no central palor |
| a slide that is too thick looks like: | stacks of cells many overlapping |
| a normal slide is: | cells randomly spaced in singles or occasional doubles |
| The round and oval red cells with diameters of greater than 9 microns and decreased central pallor are | macrocytes or megalacytes |
| RBCs that vary significantly in size are called | Anisocytes |
| cells that have MCV of < 80, & normal central pallor are called | Microcytes |
| Cells with MCV > 100, round to oval, decreased central pallor are | Macrocytes or megalocytes |
| RBCs with > Normal MCV and central pallor, larger than normal. | Pseudomacrocytes |
| Pseudomacrocytes are larger than normal due to what? | Flattening on the slide |
 |
|
|
|
|
|
|
|
||||||||
|
|
|
|
|
|
|
|
Examination of RBCsExamination of red blood cells is important to aid the physician in making a diagnosis. The features act as a QC guide for the red cell indices values for either manual or automatic evaluation. Compare visual and analytical results for report. The critical area of a smear is the thin area. If it is too thin it has a flat cobblestone appearance. It it is too thick, morphology features will not be distinguisable. A good smear has RBCs appear random, singly, with occasional doubles. Thick smears have stacks of red cells. Normal cells are round elastic, non-nucleated biconcave, and buff colored on Wrights stain. A central area of palor is 1/3 of the cell. Diameter is 6-9 micron, and averages 7.2 microns. A red blood cell is about the same size as the nucleus of a lymphocyte. RBCs are 2.1 microns thick. MCV (Mean Corpuscular Volume) normal is 87 cubic microns/femtoliter (fL). Artifactual morphology occurs when slide is too thick or too thin.Abnormal RBCsMicrocytes, macrocytes, Pseudomacrocytes, Anisocytes Normal RBCs are 6-9 microns average of 7.2. MCV is 87 cubic microns/fL 1/3 area of central palor and 2.1 microns thick, & roundMicrocytes are smaller than normal; less than 7 microns, and MCV < 80 cubic micron/fL, central area of palor is light or normal round. Macrocytes are larger than normal; between 9 & 14 microns, MCV is 100 or more cubic microns/ fL, no central palor, oval or round. Pseudomacrocytes are larger than normal; 9-14 microns, MCV normal (87), has central palor, flatend round oval. Anisocytes are an increase in size variation (RDW). MCV is normal (87), Occasionally 2 cell sizes are presented. |
Favorite Labeled Images
Spanish 3
Ch.18 LTI-MA 509
MedTemCP5 Word+Pics
HHS Shrek
Biology Lab Midterm
Buen Viaje lv.2 ch 8
BIOL3326 Forms
Spanish 3
Ch.18 LTI-MA 509
MedTemCP5 Word+Pics
HHS Shrek
Biology Lab Midterm
Buen Viaje lv.2 ch 8
BIOL3326 Forms
