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Derm Inf.Dermatoses

CM Dermatology Inflammatory Dermatoses

QuestionAnswer
Etiology of Psoriasis A systemic,immunologic,genetic disease manifesting in skin and,or joints. Many of these people have arthritis. Usually comes on in teens, young adults
Most common locations to find psoriasis Scalp (80%), elbows (78%), Legs (74%)
Psoriasis facts usually symmetric, well-demarcated borders, scaly, raised lesions, pruritis is variable, pustules may outline lesions and occur palms and soles.
Psoriasis advice soak in water to slough off, don't scrape off
Drugs that exacerbate psoriasis lithium, beta-blockers, antimalarials, systemic steroids
Factors that flare psoriasis Streptococcal infection, injury or trauma, Drugs, low humidity, emotional stress, overtreatment
Small papules of short duration (weeks to months), usually in children and young adults. DROP LIKE. 14-17% of psoriatic patients present initially and may follow a strep URI Guttate Psoriasis
Red, scaly psoriasis all over is called Erythrodermic Psoriasis
Sx and Signs of erythrodermic Psoriasis Patients are ill: hypo-,hyperthermia,protein loss,dehydration, renal and cardiac failure
Superficial pustules is suggestive of Pustular Psoriasis. Filled with neutrophils
Extracutaneous signs of Psoriasis Nails: onycholysis,yellowish staining, pitting. Mucosa: geographic tongue. Joints: 10%-30% of psoriatic patients
Psoriasis joint swelling can also look like RA, with ulnar deviation too.
Most common arthritis associated with psoriasis asymmetrical arthritis. Other types: Symmetrical arthritis (like RA), distal interphalangeal joint dz, destructive polyarthritis, ankylosing spondylitis
Inflammatory cells involved in psoriasis T-lymphocytes and cytokines
Psoriasis tx strategy Initally control dz, decrease area involved, decrease erythema, scaling, and thickness. Use topical therapy, phototherapy, systemic therapy
Topical options Anthralin, steroids, tars, vit d analogs, retinoids, taclonex ointment
dandruff is aka seborrheic dermatitis. Can occur other places than the scalp
Pityrosporum ovale is a possible causative factor of seborrheic dermatitis
Most common skin manifestation in AIDs patients Seborrheic dermatitis; often precedes AIDs symptoms. Severity often parallels clinical deterioration
Best way to remove scales in seborrheic dermatitis with fluid, gently
Seborrheic Dermatitis is associated with which neurologic disease? Parkinson's
Persistent or resistant cases of seborrheic dermatitis should be cultured for dermatophyte infection.
Tx for Seborrheic Dermatitis frequent washing, topical steroids, shampoo (change type; pyrithione zinc, tar, sulfacetamide, ketoconazole, selenium).
Common,benign,usually asymptomatic,self-limited dermatoses. Evidence of viral origin. 20% of pts have recent hx of acute infection Pityriasis rosea. muted red, and fine scale (much less than psoriasis), usually on trunk.
Collarette scale is associated with Pityriasis rosea. Fine ring of scale within a plaque
Papular lesions in pityriasis rosea are found more commonly in young children, pregnant women, and blacks. Lesions subside in 1-3 months
Pityriasis Rosea Therapy most beneficial in the first week. antihistamines, topical steroids, oral prednisone, UVB phototherapy
If you see something that looks like Pityriasis rosea but is also on the hands and soles, get an RPR to rule out syphillis
Lichen planus facts Inflammatory cutaneous and mucosal reaction pattern of unknown originMean age of onset –males 40.3 and females 46.4. Eruption clears in one year in 68% of patients and recurs 49% of the time. Liver disease is a risk factor for LP.
______ is a post-bone marrow transplant graft-vs-host reaction Lichen planus
Lacy reticulated pattern of white lines (wickham's stria) suggest lichen planus
Common locations of lichen planus flexor surfaces of wrists adn forearms, legs above the ankles. 20% of pts with lichen planus do not itch.
Common things in a ddx for red, scaly and papular lesions. Psoriasis, Seborrheic dermatitis, Pityriasis rosea, Lichen Planus, 2ndary syphillis infection
Created by: ltm12
 

 



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