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Derm Inf.Dermatoses
CM Dermatology Inflammatory Dermatoses
| Question | Answer |
|---|---|
| Etiology of Psoriasis | A systemic,immunologic,genetic disease manifesting in skin and,or joints. Many of these people have arthritis. Usually comes on in teens, young adults |
| Most common locations to find psoriasis | Scalp (80%), elbows (78%), Legs (74%) |
| Psoriasis facts | usually symmetric, well-demarcated borders, scaly, raised lesions, pruritis is variable, pustules may outline lesions and occur palms and soles. |
| Psoriasis advice | soak in water to slough off, don't scrape off |
| Drugs that exacerbate psoriasis | lithium, beta-blockers, antimalarials, systemic steroids |
| Factors that flare psoriasis | Streptococcal infection, injury or trauma, Drugs, low humidity, emotional stress, overtreatment |
| Small papules of short duration (weeks to months), usually in children and young adults. DROP LIKE. 14-17% of psoriatic patients present initially and may follow a strep URI | Guttate Psoriasis |
| Red, scaly psoriasis all over is called | Erythrodermic Psoriasis |
| Sx and Signs of erythrodermic Psoriasis | Patients are ill: hypo-,hyperthermia,protein loss,dehydration, renal and cardiac failure |
| Superficial pustules is suggestive of | Pustular Psoriasis. Filled with neutrophils |
| Extracutaneous signs of Psoriasis | Nails: onycholysis,yellowish staining, pitting. Mucosa: geographic tongue. Joints: 10%-30% of psoriatic patients |
| Psoriasis joint swelling can also look like | RA, with ulnar deviation too. |
| Most common arthritis associated with psoriasis | asymmetrical arthritis. Other types: Symmetrical arthritis (like RA), distal interphalangeal joint dz, destructive polyarthritis, ankylosing spondylitis |
| Inflammatory cells involved in psoriasis | T-lymphocytes and cytokines |
| Psoriasis tx strategy | Initally control dz, decrease area involved, decrease erythema, scaling, and thickness. Use topical therapy, phototherapy, systemic therapy |
| Topical options | Anthralin, steroids, tars, vit d analogs, retinoids, taclonex ointment |
| dandruff is aka | seborrheic dermatitis. Can occur other places than the scalp |
| Pityrosporum ovale is a possible causative factor of | seborrheic dermatitis |
| Most common skin manifestation in AIDs patients | Seborrheic dermatitis; often precedes AIDs symptoms. Severity often parallels clinical deterioration |
| Best way to remove scales in seborrheic dermatitis | with fluid, gently |
| Seborrheic Dermatitis is associated with which neurologic disease? | Parkinson's |
| Persistent or resistant cases of seborrheic dermatitis should be cultured for | dermatophyte infection. |
| Tx for Seborrheic Dermatitis | frequent washing, topical steroids, shampoo (change type; pyrithione zinc, tar, sulfacetamide, ketoconazole, selenium). |
| Common,benign,usually asymptomatic,self-limited dermatoses. Evidence of viral origin. 20% of pts have recent hx of acute infection | Pityriasis rosea. muted red, and fine scale (much less than psoriasis), usually on trunk. |
| Collarette scale is associated with | Pityriasis rosea. Fine ring of scale within a plaque |
| Papular lesions in pityriasis rosea are found more commonly in | young children, pregnant women, and blacks. Lesions subside in 1-3 months |
| Pityriasis Rosea Therapy | most beneficial in the first week. antihistamines, topical steroids, oral prednisone, UVB phototherapy |
| If you see something that looks like Pityriasis rosea but is also on the hands and soles, get an | RPR to rule out syphillis |
| Lichen planus facts | Inflammatory cutaneous and mucosal reaction pattern of unknown originMean age of onset –males 40.3 and females 46.4. Eruption clears in one year in 68% of patients and recurs 49% of the time. Liver disease is a risk factor for LP. |
| ______ is a post-bone marrow transplant graft-vs-host reaction | Lichen planus |
| Lacy reticulated pattern of white lines (wickham's stria) suggest | lichen planus |
| Common locations of lichen planus | flexor surfaces of wrists adn forearms, legs above the ankles. 20% of pts with lichen planus do not itch. |
| Common things in a ddx for red, scaly and papular lesions. | Psoriasis, Seborrheic dermatitis, Pityriasis rosea, Lichen Planus, 2ndary syphillis infection |