| Question |
Answer |
| asd |
sd |
| GENERIC NAME |
DILTIAZEM |
| BRAND NAME |
Cardizem |
| CLASS |
Calcium Channel Blocker, Calcium antagonist |
| MECHANISM OF ACTION |
Inhibits calcium ion influx across cell membranes during depolarization,decreases SA&AV conduction,dilates coronary&peripheral arteries.Slows the rapid ventricular rate associated with a-fib and a-flutter,&reduces coronary&peripheral vascular resistance. |
| INDICATIONS |
Rapid ventricular rates associated with atrial fibrillation and atrial flutter, and for PSVT refractory to adenosine. |
| CONTRAINDICATIONS |
Hypotension(less than 90 mmHg systolic), Acute Myocardial infarction, Cardiogenic shock, Ventricular tachycardia or wide-complex VT of unknown origin, Second or third-degree AV block,(WPW) syndrome, Sick Sinus syndrome, Beta Blocker Use |
| ADVERSE REACTIONS |
hypotension, Bradycardia, heart block, chest pain, and Asystole, N/V, headache, fatigue, drowsiness |
| NOTES ON ADMINISTRATION |
None |
| INCOMPATABILITIES/DRUG INTERACTIONS |
Avoid use in patients with poison- or drug-induced tachycardia. Calcium chloride can be used to prevent the Hypotensive effects of this drug and treat patients with a calcium channel blocker overdose. |
| Beta blocker use. |
|
| DOSE/ROUTE, Adult Dosage, Initial |
0.25 mg/kg IVP (usually 20 mg) administered over 2 minutes.If response is inadequate, repeat in 15 minutes; 0.35 mg/kg IVP administered over 2 minutes |
| Adult Maintenance infusion |
5.0 to 15 mg/hr |
| Pediatric Dosage |
The safety of this drug for use in children has not been established. |
| ONSET OF ACTION |
IV - immediately |
| PEAK EFFECTS |
IV - 2 hours or less |
| DURATION OF ACTION |
IV - 4 to 6 hours |
| AZ DRUG BOX SUPPLY RANGE |
25 mg,10 mg |
Biology Lab Midterm
