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CM Stroke Mngment

Stroke Management

QuestionAnswer
Stroke Risk Factors older age (every decade over age 55, risk doubles), men (more women die from stroke), AA, hispanic, obesity, alcohol abuse, smoking, poor diet/nutrition
Modifiable risk factors HTN, atrial fib, carotid stenosis, diabetes, hyperlipidemia, prior stroke, TIA
How much can weight reduction lower bp? up to 20mmHG/10kg weight loss
Single most treatale risk factor for stroke High bp
What percentage Risk Reduction is acheivable with aspirin? 22%
Warfarin vs Aspirin Warfarin has better risk reduction (45%).
CHADS pneumonic CHF, HTN, Age >75, Diabetes, Stroke of TIA. (6 possible points. 3 is high treat with warfarin. Moderate =2 points, can argue either way with warfarin. Below 2, treat with aspirin)
If CHADs score is 2 from previous stroke, tx with Warfarin.
% stenosis = 1- (A/B), what is A? A is the area of tightest narrowing. B is the normal width
What is the impact of tight glucose control on macrovascular complications? none. Macrovascular complications not affected by glucose control. Tight control of HTN is the goal.
Cholesterol and RR No evidence that lowering cholesterol overall affects stroke incidence. But if you use statins in patients with CHD, there is a risk reduction
Aspirin in low-risk pts no data to support using Aspirin. Risk outweighs benefit (bleeds). Aspirin recommended for 10-yr cardiovascular risk 6-10%
Only FDA approved therapy for pts with acute stroke IV-tPA (clot busting drug)
What is the protocol for giving tPA initiated within 3 hours of sx onset (taken from the last time the pt was known to be sx free). Head CT without evidence of hemorrhage or other complicating lesion
What are pts treated with if they are not candidates for receiving tPA? endovascular - catheter, remove clot mechanically
MERCI clot retriever Used to remove clots
Acute stroke management Temperature, Fluids/Glucose, BP, Antithrombotic agents
Cerebral Blood flow equation MAP/CVR; if you stand, MAP decreases, so CVR accomodates this by decreasing/dilating in order to keep CBF constant.
In stroke patients, CVR is constant. If MAP is decreased, then CBF decreases; there is some data to suggest that tx of antihypertensives in acute pts can be harmful. So don't treat high bp acutely
Only data available on anticoagulation in acute pts is on which drug Aspirin (when started within 48 hours) decreases recurrent events up front. Need to treat 100 pts to decrease 1 stroke
3 top complications in stroke patients UTI (11%), CHF (10% - watch fluids!), Pneumonia (10%)
DVT prophylaxis given to all stroke patients who can't get up and walk. DVT risk is 2%
Secondary Prevention Platelet antiaggregants, anticoagulants, blood pressure, lipid lowering, endarterectomy
Prior stroke patients treated with Warfarin have what type of Risk Reduction? 67% decrease in risk when treated with Warfarin
Each 10mmHg decrease in systolic BP is associated with _____% decrease in stroke risk? 28%. Do not use acutely
Motor recovery after stroke is determined by the severity of the stroke
Created by: ltm12
 

 



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