| Value |
Calculation |
Normal Range |
Clinical significance |
| BUN:Creatinine ratio |
BUN/Creatinine |
12-20 |
↑ in pre or postrenal azotemia |
| Creatinine clearance |
UxVx1.73/PxSx1440
U-urine creatinine;
P-plasma creatinine;
V-urine volume in ml per 24hr;
S-body surface
|
♂ 97-137 ml/min;
♀ 88-128 ml/min |
↑ in renal disease |
| Friedewald formula |
LDL=Total cholesterol -HDL-(tryglicerides/5) |
<130 mg/dL |
↑ in coronary artery disease;
not valid if tryglicerides >400 mg/dL |
| Calculated Osmolality |
1.86xNa + (glucose/18) + (BUN/2.8) + 9 |
275 - 295 mOsm/kg |
↑ in dehydration; uremia; diabetes; alcohol intoxication
↓ in excessive H2O intake |
| mg/dL into mmol/L |
mmol/L =(mg/dL)x 10 x valence / MW |
|
|
| A:G ratio |
albumin/(total protein -albumin) |
1-2.5 |
Reversed ratio - multiple myeloma, liver disease |
| Anion Gap |
(Na+K)-(Cl+CO2) |
10-20 mEq/L |
↑ in renal failure, diabetic and lactic acidosis, drugs, toxins, lab. error |