| Question |
Answer |
| Where are lipoproteins made? What is their job? |
intestinal mucosa and liver. These proteins are found in the plasma and transport cholesterol and triglycerides to areas of utilization and storage
|
| Definition of cholesterol? |
Dietary lipid synthesized by the body |
| Def of triglyceride? |
Dietary lipid used by body |
| What are the five types of lipoproteins?
|
Chylomicrons. VLDL. LDL. IDL. HDL. |
| What causes raised levels of lipoproteins? |
Diets high in sat fat and cholesterol. |
| Explain chylomicron. |
Large lipoprotein molecule created by absolrpion of lipids by the cells in the small intestine. They transport lipids to adipose tissue to be broken down by lipoprotein lipase. |
| Rank the 4 lipoproteins (skip IDL) from most triglyceride content to least. |
Most triglyceride is in Chylomicrons > VLDL > LDL > HDL. Least triglyceride is in HDL. So chylomicrons are all fat no muscle (protein) |
| Rank the 4 lipoproteins (skip IDL) from most protein content to least. |
HDL has most protein > LDL> VLDL > Chylomicron
So HDLs are all muscle (protein) and little fat. |
| Rank the 4 lipoproteins (skip IDL) from most cholesterol content to least. |
LDL have a lot of cholesterol > HDL > chylomicron |
| Purpose of drug treatment |
decrease in plaque formation and regression of existing plaque |
| 4 MOA of antihyperlipidemics |
1. decrease Lipoprotein production
2. Increase degradation
3. Increase cholesterol removal
4. Decrease absorption from other sources |
Biology Lab Midterm
