| Question |
Answer |
| which drugs cause pulmonary fibrosis? |
busulfan bleomcyin amiodarone |
| which drugs cause gyneomastia |
"Some drugs create awesome knockers" spironolactone digitalis cimetidine alcoholism ketoconazole (estrogen) |
| which drugs cause SLE like syndrome |
"it's not HIPP to have lupus" hydralazine inh procainamide phenytoin |
| which drugs --> osteoporosis |
CHO corticosteroids heparin |
| which drug --> gingival hyperplasia |
phenytoin |
| which drugs --> photosensitivity |
Amy played Tetris on her cell phone in the sun amiodarone sulfonamides tetracycline |
| which drugs --> tendonitis and tendon rupture in kids |
fluoroquinolones |
| which drug --> gray baby syndrome |
chloramphenicol |
| which drugs --> agranulocytosis |
colchicine carbamazepine clozapine |
| which drugs --> atropine like side effects |
tricyclics |
| which drugs --> cardiac toxicity |
Dawn sat on the Docks mending her red, broken heart doxorubicin daunorubicin |
| which drugs --> torsades de pointes |
Ia and III aniarrhytmics cisapride |
| which drugs --> focal/massive hepatic necrosis |
Hello Val! Have a seat before your liver dies! halothane valproic acid acetaminophen |
| which drug --> fanconi's syndrome |
expired tetracycline |
| which drug --> interstitial nephritis |
methicillin |
| which drugs --> hemorrhagic cystitis |
cyclophosphamide ifosfamide |
| which drug --> hepatitis |
INH |
| which drugs --> pseudomembranous colitis |
I have to take a CLAMP clindamycin ampicillin |
| which drugs --> nephrotoxicity AND ototoxicity |
"if you call, i won't be able to hear you in the bathroom" Cisplatin aminoglycoside loop diuretics |
| which drugs --> seizures |
buproprion imipenem clistatin |
| which drugs --> DI |
lithium demeclocycline |
| which drugs --> aplastic anemia |
chloramphenicol benzene NSAIDS |
| which drug --> coronary vasospasm |
cocaine |
| which drugs --> flushing |
AIDEN was in the VAN FLUSHING NIACIN and CALCIUM niacin CCB adenosine vancomycin |
| which drug --> hemolysis in G6PD pts |
sulfonamides INH aspirin ibuprofen primaquine nitrofurantoin |
| whch drugs --> acute aholestatic hepatitis |
macrolides |
| which drugs --> cinchonism |
quinidine quinine |
| which drugs --> disulfiram like rxn |
metronidazole some cephalosporins procarbazine sulfonylureas |
| which drug --> neurotoxicity/nephrotoxicty |
polymyxins |
| uses for cytarabine |
AML |
| examples of nitrosureas |
"you MUST not let the Nitro go to your head, or you'll do a strip tease- a sin!" carmustine lmoustine semustine streptozacin |
| uses for nitrosureas |
brain tumors (incl. GBM) |
| uses of the -platins |
Platinum treated BOLTs breast ovarian lung testicular |
| uses for busulfan |
"I will bustle to treat my dark CaMeL" CML |
| adverse effects of busulfan |
"I will bustle to treat my DARK CaMeL" hyperpigmentation pulmonary fibrosis |
| uses for rubicins |
"MS. Hodgkin's will LOB the RED ball" myeloma sarcoma Hodkin's lung ovarian breast |
| uses for dactinomycin |
"children ACT out" rhabdomyosarcoma wilm's tumor ewing sarcoma |
| MOA 6MP |
blocks do novo purine synth, activated by HGPRTase |
| which 2 drugs work synergistically with each other to prevent DNA replicaion? |
5-FU MTX |
| MOA MTX |
blocks DHF reductase, preventing DHF --> THF |
| MOA 5FU |
blocks thymidylate synthase (preventing dUMP --> dTMP) |
| which cancer agen has minimal myelosuppression? |
bleomycin |
| leucovorin |
folinic acid that can reverse some of the myelosuppression associated with MTX (doesn't do anything for 5FU myelosuppression) |
| "rescue agent" for 5FU |
thymidine |
| which cancer agent --> macrovesicular fatty change in liver? |
MTX |
| cancer agents that alkylate DNA |
Busulfan Platins Nitrosureas cyclophosphamide/ifosfamide |
| which alkylating agent requires bioactivation |
nitrosureas |
| uses for -phosphamides |
non-hodgkin's breast ovarian |
| which drugs intercalate in DNA? |
3D doxorubicin daunorubicin dactinomycin |
| which cancer agents generate free radicals |
doxorubicin daunorubicin bleomycin |