| Question |
Answer |
| This adult tumor crosses the Corpus Collosum, stains for GFAP, and has tumor cells bordering areas of necrosis and hemorrhage on Light microscopy |
Glioblastoma Multiforme (Grade IV Astrocytoma) |
| This adult tumor has concentric arranged calcifications, and arises from arachnoid cells external to the brain. |
Meningioma |
| This adult tumor is S-100 Positive, and commonly occurs in the cerebellar pontine angle, bilaterally in neurofibromatosis 2 (chromosome 22) |
Schwannoma |
| This adult tumor is often in the frontal lobes, and has round nuclei with clear cytoplasm that is often calcified. You may see a chicken wire capillary pattern |
Oligodendroma |
| This Adult Tumor is often prolactin secreting, causes bitemporal hemianopsia, what is its origin? |
Rathke's Pouch (its a pituitary adenoma) |
| This childhood tumor is well circumscribed and contains eosinophilic corkscrew fibers. |
Pilocytic Astrocytoma. Low grade |
| This childhood tumor is most often in the cerebellum, and contains rosettes or pervivascular pseudorosettes, and can cause hydrocephalus. It is a form of a primintive neuroectoderm tumor |
Medulloblastoma. |
| This tumor is often in the 4th ventricle, and has characteristic rod shaped basal ciliary bodies found near the nucleus, as well as pervascular pseudorosettes |
Ependyoma |
| This childhood tumor is often in the cerebllum, and contains foamy cells and is rich in vasculature. What chromomome is likely altered and what hematological finding will be present? |
Chromosome 3 - Von Hippel Lindau, and you will find polycythemia due to increased EPO. The tumor is a Hemangioblastoma |
| This childhood tumor also causes bitemporial hemianopsia, and has calcifications. What is it derived from? |
Rathke's pouch - Craniopharyngioma. |
| Top 5 Childhood brain tumors ordered by descending incidence |
1.) Pilocytic (low grade) astrocytoma
2.) Medulloblastoma
3.) Ependymoma
4.) Hemangioma
5.) Craniopharyngioma |
| Top 5 Adult brain tumors ordered by descending incidence |
1.) GBM (grade IV astrocytoma)
2.) Meningioma
3.) Schwannoma
4.) Oligodendroglioma
5.) Pituitary adenoma |
| Location of most childhood brain tumors |
infratentorial |
| Location of most adult brain tumors |
supratentorial |
| Half of all adult brain tumors are |
metastases |
| Trigger words:
Spindle cells, whorled pattern, psammoma bodies |
Meningioma |
| Trigger words:
Aything associated w/NF 2 |
Schwannoma |
| Trigger words:
pseudopalisading, butterfly, GFAP stain |
Glioblastoma Multiforme |
| Trigger words:
fried egg |
Oligodendroglioma |
| Trigger words:
Rathke's pouch - adult tumor?
Rathke's pouch - childhood tumor? |
Pituitary adenoma
Craniopharyngioma |
| Trigger words:
Foamy cells |
Hemangioblastoma |
Beef Production
