| Drug |
Trade Name |
Indication |
Contraindications |
Dosage |
Side Effects |
Precations, Other info. |
Class |
| Thiamine |
Vitamin B1 |
coma of unkown origin;coma involving alcohol;alcohol-induced B1 deficiency.delirium tremens |
none significant |
100 mg IV or IM |
almost none |
give before Dextrose especially in Alchoholics |
Vitamin (B1) |
| Dexamethasone |
Decadron, Hexadrol |
cerebral edema |
|
|
|
|
corticosteroid |
| Mannitol |
Osmotrol |
acute cerebral edemablood transfusion reactions |
|
|
|
|
osmotic diuretic |
| Methylprednisolone |
Solu-Medrol |
spinal cord injury |
|
|
|
|
corticosteroid |
| Diazepam |
Valium |
major motor seizuresstatus epilepticuspremedication (e.g. cardio versionskeletal muscle relaxantacute anxiety states |
hypersensitivity |
(slow IVP)5-10 mg for seizures2-5 mg for acute anxiety |
hypotensiondrowsinessheadacheamnesiarespiratory depressionblurred visionnausea/vomiting |
incompatible with many other medsflush IV line well before using other medsshould not be used in conjunction with alchol and other CNS depressants |
anticonvulsant/sedative (benzodiazepine) |
| Lorazepam |
Ativan |
anxietystress |
|
|
|
|
anticonvulsant/sedative (benzodiazepine) |
| Midozolam |
Versed |
premedication for medical proceduresseizures,sedation |
allergy; hypotension; respiratory deressioncoma |
|
|
|
anticonvulsant/sedative, hypnotic, (benzodiazepine) |
| Phenytoin |
Dilantin |
major motor seizuresstatus epilepticusdysrhythmias caused by digitalis toxicity |
|
|
|
|
anticonvulsant/antiarrhythmic |
| Fosphenytoin |
Cerebryx |
|
|
|
|
|
|
| Phenobarbital |
Luminal |
major motor seizuresstatus epilepticusacute anxiety states |
|
|
|
|
|
| Pancuronium |
Pavulon |
temporary paralysis where ET is indicated & muscle tone, seizures, or laryngospasm prevents it |
|
|
|
|
|
| Dexamethasone |
Decadron, Hexadrol |
cerebral edemaanaphylaxisasthmaexacerbation of COPD |
|
|
|
|
|
| Succinylcholine |
Anectine |
temporary paralysis where ET is indicated & muscle tone or seizure activity prevent it |
|
|
|
fasciculations |
depolarizing neuromuscular blocker (short-acting) |
| Insulin |
Humulin, Novolin, Iletin |
Type I diebetes |
|
5-10 Units |
|
Regular (fast-acting) |
|
| Glucagon |
|
Hypoglycemia |
Known sensitivity |
1 mg IM ( can be given IV in smaller doses) |
|
only useful when adequate liver glycogen stores existNot recommended for pediatric patients |
hormone/anti-hypoglycemic |
| Dextrose |
D50W |
hypoglycemia (severe brain injury occurs if prolonged)Coma of unknown origin. |
none significant |
25 grams (50 ml of 50% solution)pedi- 0.5 to 1.0 gm/kg (D25W)slow IV push |
tissue necrosis & Phlebitis |
blood glucose reading prior to giving.Use larger vein |
carbohydrate |