| Question |
Answer |
| Receptor |
a cellular factor that recognizes and binds a specific ligand to induce a response |
| Ligand |
a molecule bound by another molecule such as a receptor |
| Intercellular Signaling Molecule |
nutrient ligand secreted by one cell to induce a response in another cell |
| Hormone |
intercellular signaling molecule that controls metabolism or physiology |
| Growth factor |
intercellular signaling molecule that controls cell cycle progression, cellular differentiation, or morphogenesis during development |
| Cytokine |
growth factor involved with hematopoiesis |
| Isoreceptors |
different receptors bound and activated by the same ligand, often inducing distinct responses in different cells |
| Paracrine |
for an intercellular signaling molecule to diffuse over a short distance, usually through interstitial spaces, to induce a response |
| Endocrine |
for an intercellular signaling molecule to diffuse through the blood |
| Hydrophobic Ligands |
Steroids (cholesterol derivatives)
Fatty acid derivatives (prostoglandins, retinoic acid)
|
| Hydrophilic Ligands |
Amino acid derivatives (catecholamines-tyrosine, histamine-histidine, serotonin-tryptophan)
Peptides and proteins (insulin, glucagon, FSH, TGFβ, etc.)
Nucleotides (cAMP)
No carbohydrates - this is the only major class of biochemicals not used as recept |
| Transport proteins |
action potential initiation & propagation
|
| Serine/threonine Kinases |
Tissue Differentiation
Tissue Patterning
Immunosuppression
Cell Cycle progression
|
| Seven Receptor Transmembrane |
blood glucose levels
metabolism
menstrual cycle
inflamation
glycogenolysis |
| Tyrosine Kinases |
blood glucose levels
metabolism
cell proliferation
cell cycle progression
differentiation
apoptosis.
glycogen synthesis |
| TGF-b |
Tissue Differentiation
Tissue Patterning
Immunosuppression
Cell Cycle progression |
| Ras |
TYROSINE KINASES
metabolism
glycogen synthesis
blood glucose levels
cell cycle progression
apoptosis.
differentiation |
| Phosphoinositide |
TYROSINE KINASE
cell proliferation |
| cAMP |
SEVEN TRANSMEMBRANE RECEPTOR
blood glucose levels
metabolism
glycogenolysis
menstrual cycle
inflamation
|
| synaptic ligand-gated ion channels |
TRANSPORT PROTEINS
action propagation initiation & potential |
Buen Viaje lv.2 ch 8
