| Question |
Answer |
| What is the whole blood percentage of plasma? |
~55% |
| What is the percentage of whole RBCs in plasma? |
~45% |
| What is the buffy coat? |
White blood cells and platelets |
| Cutaneous vasculitis |
inflammation of the blood vessel walls |
| Plasma Proteins |
Albunin, globulins and fibrinogens |
| Albumin |
Provides osmotic pressure to the blood |
| Globulins |
antibodies used for immunity |
| Fibrinogen |
-converted to fibrin with blood clots
-serum = plasma w/o clotting factors |
| 4 Characteristics of RBCs |
1. No "organelles"
2. No nucleus
3. Bi-concave
4. Hemoglobin carries |
| Hereditary Spherocytosis |
inherited disorder
-defects in RBC membrane
-spheroidal, less deformable cells
-spectrin deficiency which makes teh cells non-biconcave |
| Granulocyte |
-WBC
-4x the size of RBC
-Polymorphonuclear |
| Eosinophils |
-WBC
-Nucleus surrounded by crystals |
| Erythropoiesis |
RBC Production |
| Granulopoiesis |
Granulocyte Production |
| Aplastic anemia |
-Decrease in cells of bone marrow
-Decrease in RBC or Platelets
|
| megakarycyte |
parent of platelet
-peels off parts of itself to become platelets |
| Leukemia |
Cancer of white blood cells |
| Monocyte |
Kidney shaped nucleus
Nucleus pushed aside by organelles
largest WBC |
| Lymphocytes |
Memory cells
T and B cells only look different out in tissues where they are secreting antibodies |
| Basophils |
Hardest to find
Dark,dark blue granules |
| Agranulocytes |
Lymphocytes and monocytes |
| 5 White Blood Cells |
Lymphocytes
Monocytes
Neutrophil
Eosinophil
Basophil |
| RBC |
Erythrocyte |
| Hemocrit |
Portion of blood occupied by red blood cells |
| Von Willibrand Disease |
Attractant for clotting is insufficient.
Plenty of platelets...nothing to attract them |
| Erythrocyte Formation |
Red Bone marrow |
| Agranulocytes |
Monocytes, Lymphocytes |
| Granulocytes |
Neutrophils, Eosinophils, Basophils |
| Reticulocyte |
RBC without nucleus BUT not yet concave |
| Neutrophils |
Phagocytic Cells, first line of defense. Segmented Nuclei (2-4 lobes). |
| Basophils |
Less than 1%. Contains Herparin and histamine. Involved in hypersensitivity reactions |
| Eosinophils |
They increase in number in allergic reactions and in parasitic infections. 2-4%. Bilobed nucleus. |
| Lymphocytes |
T Cells, B Cells, NK Cells. 20-40% of Leukocytes. |
| T Cells |
1) aid the B cells in
their response to an antigen (Helper T cells), 2) help regulate the immune response
(Suppressor T cells) and 3) kill other cells (Cytotoxic T cells). |
| B Cells |
cells that in the connective tissues develop into plasma cells
and produce antibodies (immunoglobulins) |
| Platelets |
Cell fragments that are involved in blood clotting |
| Hematopoiesis |
Blood formation |
HHS Shrek
