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Pharmaceutical Equivalents. Drug products are considered pharmaceuticalequivalents if they contain the same active ingredient(s), are of the samedosage form, route of administration and are identical in strength orconcentration (e.g., chlordiazepoxide hydrochloride, 5mg capsules).
Therapeutic Equivalents. approved as safe and effective, pharmaceutical equivalen( identical amount of active drug ingredient in the same dosage form and route of administration), bioequivalent
bioequivalent rate of absorption is the same
where should you look to find out if a generic is available? facts and comparisons, the stock shelf and the orange book
where should you look to find out if this product is interchangeable orange book
if the rating starts with an A mena that the drugs are therapeutically equivalent and may be interchanged. all A rated drugs are considered interchangeable regardless of the second letter
what is meant by B rated? or the first leter begins with B not shown to be therapeutically equivalent and may not be interchanged
the 4 most common routes intradermal (ID), Subcutaneous (Subcut), Intramuscular (IM), and Intravenous (IV)
Max volume for ID 0.1 ml
Max volume for Subcut 2 ml or less
Max volume for IM 2.5 ml
Max volume for IV No volume restriction over time
route for diagnostic purposes ID
route for slow onset and not well absorbed Subcut
when need to give solution or suspension IM
when need a slower onset of action than IV but need to give 2.5ml IM
when need 100% absorption IV
common site for chemotherapy intra-arterial-arteries
common site for steroids into a joint space Intra-articular
common site for Epinephrin intracardiac
injection site into join FLUID intra-synovial KEY IS fluid and not space
common site for narcotics epidural
Needle lenght for ID and SC are tipicaly 1/2, ID can be smaller 1/4
ID gauge size is 27 gauge, remember can't put much in so don't need large opening/gauge is thickness
SC gauge sizes 28 to 30
IM gauge size 20-25
IV gaauge size 14 to 20
advan of IV immediate response, delivery stopped imm
disadv of IV incre in time for adm, infect, cost, ...
complicantions of IV phlebitis, thromphlebitis, infiltration, and extravastation
vesicant drug leaks extravasation
iv fluid leaks infiltration
clot formation thrombophlebitis
inflammation of vein phlebitis
SVP <250 small volume parenteral
LVP >250 large vol parenteral
Created by: lainylaina
 

 



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