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Stack #125227
| Question | Answer |
|---|---|
| what is the common intermediate that enters into the CAC cycle from amion acid, fatty acid, and glucose | acetyl-CoA |
| the citric acid cycle (CAC) is ____ catabolism | aerobic |
| The CAC is ofter thought of as a 3 stage process | 1. oxidative decarboxylation of pyruvate, yielding Acetyl CoA 2. acetyl CoA oxidation (the actual cycle) 3. Electron transfer and oxidative phosphorylation |
| the pyruvate dehydrogenase complex which is cluster of manycopies of enzymes) is made of what | 3 enzymes, 2 regulatory proteins (kinase, phosphotase), 5 cofactors, example of substrate channeling, very exergonic, and output is acetyl CoA, 2 e-(NADH) and CO2 |
| if you have a deficiency in thiamine it will cause problems with what cofactor | TPP thiamine pyrophosphate |
| deficiency with roboflavin cause problems with what cofactor | FAD |
| dificiency with pantothentate will cause problems with what cofactor | Coenzyme A |
| Acetyl CoA is a thioester with larger -delta G of hydrolysis | (blank) |
| Fatty acids as storage fuels have ____energy density, they are water soluble, have ____osmolarity, little water of hydration (extra weight) and chemically inert | high energy density and low osmolarity |
| some problems associated with oxidation of fatty acids are | need to be emulsified for transport, need specialized proteins to carry them, need to break relatively strong bonds |
| oxidation of Fatty acid can happen two ways (Beta and Omega) what is the difference | beta is most common and starts by the carboxly group the beta carbon |
| where does the glycolysis happen | cytosol |
| Where does the Kerbs happen | mitchondria |