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Viruses

Test #1

QuestionAnswer
General Characteristics of Viruses -very small 10-14nm
What is an intracellular parasite? -can only reproduce within living host
Discuss host specificity. -most cells are host-specific (infected only one or a few species of hosts) Example: HIV
Describe the structure of viruses. -individual units of virus are called virions or particles
What are viroids? -infectious particles, made of RNA only; can infect plants
What are prions? -infectious particles, made of protein only; can infect animals
General Characteristics of Viruses -considered to be “semi-living”→ they have some of the characteristics of life: NOT made up of cells; are much less complex (macromolecules); are able to reproduce only with considerable help from the host; have NO metabolism
General Characteristics of Viruses -are obligate intracellular parasites (can only reproduce w/in living hosts); will not grow on artificial media
General Characteristics of Viruses -do exist outside of host cells
General Characteristics of Viruses -have a high mutation rate
Discuss tissue specificity. -most viruses are tissue-specific
Host Range all of the host species that a pathogen can infect
Structure of Viruses -individual units of virus are called virions or particles
Structure of Viruses -every virus has a core of nucleic acid (genetic material)→either DNA or RNA→ never both; either single or double stranded
Structure of Viruses -every virus has a coat of protein(capsid) around the nucleic acid
Structure of Viruses -some viruses have an outer envelop of fat & protein surrounding the protein→ the envelop is at least partially derived from the host cell membrane
What are bacteriophages? -viruses that infect bacteria (aka phage)→ often used in research for studies on genetics, & learning about viruses because they are easy to grow
Latent Viral Infection -the virus remains in the host without producing symptoms & there is little or no detectable virus until reactivated later Examples: all herpes viruses
Persistent Viral Infections -the viruses reproduce but slowly &over a very long period of time; gradual increase in the # of viruses over a long period of time Examples: AID dementia caused by HIV
Relationship between Viruses and Cancer -some human (and many animal) cancers are known to be caused by viruses called oncogenic viruses Examples: Leukemia
Relationship between Viruses and Cancer -development of cancer also involves oncogenes & tumor suppressor genes & immune deficiency
Body Defenses against viral infections -immunization: best way of preventing infections; interferon’s: protein messengers produced by virally infected cells to alert neighboring cells to produce anti-viral proteins; antibodies, T cells
Created by: lisaanne11
 

 



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