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Stack #108798
| Question | Answer |
|---|---|
| an eye that does nto blink can accommodate a maximum of about __uL of liquid and ___after it blinks | 30, 10 |
| a single drop of opthalmic solution is about | 50ul that is based on 20 drops/ml so much of the dose is lost but this is common occurance |
| extend corneal contact time by the use of viscosity and thickening agents are nice because they | decrease frequency of dosing, increase the ocular retention time, and increase the bioavailibility |
| the preparation of solutions ans suspensions for ophthalmic use requires special consideration with regard to | sterility, preservation, isotonicity, buffereing, viscosity, ocular bioavailablity, and packagin |
| the prefered method to sterilize ophthalmics is _____ at 121 degrees for 15 mins | autoclaving |
| if thermal instability is a factor an alternative such as ___ may be used | bacterial filters |
| two perservative used in multi use vials in opth are | benzalkonium chloride and benzathonium chloride |
| body fluids have osmotic pressure corresponding to that of a ___solution of sodium chloride | 0.9% |
| hypertonic solution added to the eye will do what with water | tendency to draw water from eye towards the solution in an effort to dilute and estblisha concetration equilibrium |
| a hypotonic solutions placed into the eye will | draw water from site of an ophthalmic application through the tissue of the eye |
| an E value is the amount of NaCl which has the same osmotic affect as | one gram of the drug. put another way if evalue was 0.12 the drug is 12% as effective as an equal weight of sodium chloride in contributing to tonicity |
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