Question | Answer |
Women <21 yo w/ASCUS or LSIL | repeat pap in 12 mos |
Women <21 yo w/ HSIL | colposcopy +/- cytology |
Adult women w/ASCUS | repeat cyto (6 & 12 mos), HPV DNA, and colposcopy |
Adult women w/ASCUS-H | colposcopy; if neg: cyto (6 & 12 mos), HPV DNA q 12 mos |
Adult women w/ LSIL | Colposcopy, then endometrial bx. If no CIN: repeat Pap in 6 & 12 months and HPV DNA in 12 months |
Adult women w/ HSIL, CIN-2, CIN-3, or CIS on Pap: | Colposcopy & bx. Outside cervix: LEEp or cryotherapy. Inside cervix: cone bx. |
Adult women w/ AGC | endomet/endocerv bx, then colpo |
Tx of cervical abnormalities | Cyrotherapy of Cervix; LEEP; Laser; Cervical Conization |
Risks of tx of cervical abnormalities | Antibodies to sperm; Cervical Stenosis; Incompetent Cervix; Missing a significant lesion |
most common symptom of endometrial neoplasia: | AUB |
indications for endometrial ca testing | AUB >35-40 yo; AGC on Pap (also needs Colposcopy); Benign Endometrial Cells on pap if woman post menopausal |
endometrial ca RF | Postmenopausal; FH/PMH ca (ov, BrCa, colon, endomet); Tamoxifen; PCOS; Obesity; Estrogen Tx w/o progestin; Prior Endometrial Hyperplasia; DM |
endomet bx advantages | in office; minimal dilation; anesthesia not req; prophylactic Abx not req; low cost |
endomet bx CI | PG; infxn; diathesis, cerv stenosis or ca (refer) |
endomet bx: most common AE: | Cramping |
average uterine length = | 6-8 cm |
Simple/Complex Endometl Hyperplasia: causes unopposed estrogen: Premenopause | Obesity; PCOS; eating disorders; Thyroid; Herbals; other anovulation |
Simple/Complex Endometl Hyperplasia: causes unopposed estrogen: Postmenopause | Obesity; HRT; herbals w/estrogen (soy); Ovar/ adrenal estrogen producing tumor |
Endometrial hyperplasia w/o atypia: tx | Provera; Micronized Progesterone; if HRT is resumed, resume at higher dose progestin for longer time, repeat bx 3-6 mos |
When & how often should women get Paps? | Q2 yrs starting at age 21. Q3 yrs (+HPC) if Pap neg & HPV neg, starting at age 30 |
If SCC found on Pap: | resection, and/or chemo or radiation |