Question | Answer |
wha is the weight os hgb? | 1/3 of cell |
how biconcave shaped help rbs? | increse surface area to volumen ratio |
what biconcave shaped give to rbc? | a flexible shape for narrow passage capillaries |
how new rbc enter the circulation? | at rate of 2 million second |
how many hgb molecule per rbc? | 250-280 million hgb |
how heme(fe)combine? | creversible with one oxigen molecule |
how many billion atoms of oxigen in ech rbc? | 2 billion atoms of oxygen. |
what hgb level and total number of rbc indicate? | oxygen carry capacity of blood/decresed level=getting tired. |
what hgb carries? | both oxygen and carbon dioxide. |
where oxigen is attach? | to iron of the heme of the hgb. |
where carbon dioxide is attach? | amino acid /globin part of hgb. |
more epo=? | decrese perfusion=flow incre blood presion. |
how worn out cells are remove by? | fixed the macrophages in the spleen and liver. |
where the recycled occurs? | liver and spleen. |
the globin portion is broken down into? | amino acids and recycle. |
how hemo portion is split? | into iron and biliverdin (green pigment. |
where iron transpor in blood attach to? | tranferrin protein. |
where iron in blood is stored? | liver,muscle,spleen and bone marrow /to be used for synthesis /decre fe=anemic,eat more iron/ice cube. |
how biliverdin are converted to? | bilirubin(yellow) |
where bilirubin is transported? | liver and secreted into bile. |
what happen to exessive rbc destruction? | jaundice(yellow skin). |
what is erythropoiesis? | production of rbc. |
what is proerythroblast? | first baby red blood cell. |
what step going 1-4 in erythropoiesis? | -reticulocyte escape-rbc form 5-7 days-proerythroblast star prod hgb-reticulocyte form. |
what is the normal count of reticulocytes of circulating rbc? | 5% to 1.5% of circulating rbc. |
low count of reticulocyte due to? | leukemia(too many wbc),nutricion deficiency oir failure of red bone marrow(b-12,iron,not enoutgh rbc) to respond to ery thropoietin stimulation. |
hight count of teticulocyte? | indicate recent bood loss or successful iron therapy. |
how reticulocyte count lead? | low rbc /need more vitamin b-12 and iron. |
what is tisasue hypoxia is? | low oxygen due to high altituder or lower oxygen pressure cause anemia, low rbc production. |
how kidney and liver respond in tissue hypoxia? | by releasing erythropoietig(make more rbc) |
by kidney and liver respond speed up development of? | proerythroblast(baby first blood cell)into reticulocyte increase mature rbc. |
proerythroblasts?? | first baby red blood cell/mature cell. |
erythropoietin? | troduction of rbc. |
reticulocytes? | count of circulation of rbc. |