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Pharm 31 Anti

LECOM Pharm 31

MOA of sulfonamides PABA analogue that inhibits microbial dihydropteroate synthase, preventing folic acid synthesis
You can’t use Dapsone in a Pt with G6PD deficiency
PABA analogue used in susceptible vaginal infections sulfanilamide
PABA analogue used against Toxoplasmosis sulfadiazine
What to avoid using with sulfonamides Sunscreen AKA PABA
6 serious side effects of sulfonamides kernicterus in newborns, crystaluria, SJ syndrome, agranulocytosis, aplastic anemia, hepatic failure
PABA analogue used with Leprosy and dermatitis herpetiformis dapsone
7 serious SE of dapsone Hemolytic anemia, methemoglobinemia, TEN, erythema nodosum, pancreatitis, toxic hepatitis, peripheral neuropathy
Selectively inhibits bacterial DHFR trimethoprim
Selectively inhibits parasitic DHFR pyrimethamine
2 drugs used together to treat toxoplasmosis sulfadiazine/pyrimethamine
3 serious SE of trimethoprim and pyrimethamine SJ syndrome, leukopenia, megaloblastic anemia
Selectively inhibits mammalian DHFR methotrexate
Created by: csheck