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NRS 572 29, 70
Drug Drill pain, cox inhib, NSAID, acetaminophen
| Question | Answer |
|---|---|
| analgesic, antipyretic, hepatotoxic, no COX-1 SEs | acetaminophen |
| COX-1, 2 inhib, cardioprotective, stroke prevention, Reyes, hypersensitivity must avoid all NSAIDs | acetylsalycilic acid (ASA) |
| less COX-1,2 SEs with less cardioprotection bwo of reversible platelet effect | non-acetyl salicylates |
| name 5 non-acetyl salicylates | (sodium, choline, magnesium, choline/magnesium)salicylate and salicylate |
| short acting, IV available, non-selective NSAIDs | ibuprofen, ketorolac |
| long acting non-selective NSAIDs | naproxen, piroxicam, oxaprozin |
| naproxen | long acting non-sel NSAID |
| piroxicam | long-acting non-sel NSAID |
| oxaprozin | long-acting non-sel NSAID |
| Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed | meloxicam, nabumetone |
| meloxicam | Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed |
| nabumetone | Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed |
| non-selective NSAID, less GI ulceration | etoldolac |
| Misc nonselective NSAID | meclofenemate |
| Misc - topical patch/gel/hepatotoxic | diclofenac |
| misc-salicylate deriv that metabolizes into this class | diflunisal |
| COX-2 inhibitor | celecoxib |
| celecoxib SEs | predisposed to platelet mediated clotting thrombus (non-cox-1 mech). same renal SE. lessened GI, Cox-1 platelet mech) |
| does celecoxib offer cardioprotection | nope |
Created by:
lorrelaws
on 2012-03-25