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Micro 24 CNS

LECOM Micro CND infections

Virus(3) that can invade CNS via peripheral nerves HSV, VZV, Rabies
CSF: +lymphocytes(T-cell predominant)+monocytes CLEAR Virus Aseptic meningitis
CSF: +PMNleukocytosis, ++proteins Turbid pyogenic bacteria septic meningitis
Gram- diplococcus polysaccharide capsule, pili, IgA protease, endotoxin, droplet spread N. Men
N. meningitidis Serotypes in America B, C, Y
N. Meningitidis serotypes in poor countries A & W135
N. meningitidis serotype there is no vaccine for B
Petichial, maculopapular rash on extremities, fever, sore throat, photophobia N. meningitidis
N. Meningitidis treatment and post treatment/family Pen/ampicillin then rifampin
Gram – coccobacillus hard to see in stain capsul, IgA protease, pili, endotoxin H.I.b
H.I.b treatment – prophylaxis Ampicillin or ceftriaxone HIb polysaccharide vaccine
Gram + cocci, capsule, IgA protease, no pili, Strep. Pneumococci
Strep. Pneumococci treatment Vancomycin AND ceftriaxone or cefotaxime
Gram + coccobaccillus, infecting immunocompromised & neonate Listeria Monocytogenes
L. monocytogenes treatment Amp/gent
Common bogs of neonatal meningitis Group B hemolytic Streptococci & E.coli
Capulate yeast, India Ink stained, in immune suppressed or AIDS, +culture C.neoformans
Treatment of Cryptococcus neoformans meningitis Amphotericin B AND Flucytosine
SW/Mexico/South America, no CSF or culture, serum compliment-fixing antibodies Coccidiodes
Well person, acute onset, after opening dirty pool, CSF slow motile amebae Naegleria
Immunocompromized, encephalitis, only in brain biopsy Acanthamoeba
Naegleria treatment Amphotericin B, miconazole, Rifampin
Ss RNA virus, HA, F, spasms, paralysis, death, Negri bodies rhabdo virus Lyssavirus Rabies
Eye damage, hydrocephalus, intracerebral calcifications Toxoplasm Gondii
Convulsions, coma, fever, African children Plasmodium Falciparum
Granuloma in the eye or brain, has cat or dog, + ELISA Ab Toxocara
Sheep hearderliver, lung brain, kidney cyst Echinococcus granulosus
Uncooked pork, cysts in muscle, brain or eye Cysticercosis
Muscle spasm ridged paralysis, sympathetic overdrive, sweating C. tetani
Descending weakness and paralysis, vertigo, respiratory failure C. botulinum
Created by: csheck