Gases, nutrients to the tissues, waste products from the tissues and hormones
Regulates
pH of body, amount of fluid in tissues, and body temperature
Protects
Against pathogens and blood loss
Blood plasma
Liquid portion of unclotted blood
Plasma proteins
Proteins found in plasma including albumins, globulins, and fibrinogens
Albumins
Help regulate blood pressure
Globulins
Help with transport and immunity
Fibrinogens
Assist in blood clotting
Blood serum
Liquid portion of clotted blood, Plasma with fibrinogen and other clotting factors removed so blood clotting is minimized
Formed elements
Blood cells and platelets
Blood is ___% plasma
55
Blood is ___% leukocytes and thrombocytes
<1
Blood is ___% erythrocytes
45
Plasma is ____% water
90
Plasma is ___% proteins
8
Plasma is ___% acids and salts
2
Red blood cells
Biconcave, disk-shaped cells without a nuclei, constitute about 45% of whole blood, depending on gender, have a life span of about 120 days
Erythrocytes
Red blood cells
Hemoglobin
Oxygen carrying molecule made from iron, found in erythrocytes
Leukocytes
White blood cells
White blood cells
Cells responsible for the body's defenses
Throbocytes
Platelets
Platelets
Cell fragments without nuclei that assist in clotting, have a life span of about 9 days
Hemostasis
Process of blood clotting starting with muscle contraction in response to injury, proceeds to platelet plug formation and ends with blood clot formation
Contraction
Smooth muscle of the blood vessel constricts when damaged or cut
Platelet plug
Platelets in the region of damage become sticky and bind together with other platelets, blood cells, and the walls of the vessel
Blood clot
Prothrombin is converted into thrombin, fibronigen into fibrin and fibrin threads form the clot
Thrombin
Enzyme that causes blood to clot by catalysing the conversion of the soluble protein fibrinogen to the insoluble fibrin
Prothrombin
Plasma protein, one of the coagulation factors and the precursor of thrombin, prothrombin is synthesized in the liver with the help of vitamin K
Fibrinogen
Substance present in blood plasma that causes blood coagulation
Fibrin
White, insoluble protein formed by the chemical fibrinogen to form blood clots
Antigen
Protein bound to surface of a cell, gives the cell identity
Antibody
Component of immune system that attaches to a specific antigen, binds cells with other similar cells which prepares cells for phagocytosis, the body produces antibodies only for foreign antigens
Immunoglobulin
Antibody
Opsonization
Process whereby opsonins make an invading microorganism more susceptible to phagocytosis
Blood transfusion
Infusion of red blood cells into a living body, requires blood typing to match recipient with appropriate donor
Endocardium
Inner layer of the heart, composed of epithelial and connective tissues
Myocardium
Thick middle layer of the heart, composed of cardiac muscle tissue that contracts regularly
Epicardium
Outer covering or membrane of the heart, composed mostly of connective tissue
Pericardium
Loose-fitting sac around the heart, composed of serous membranes
Right atrium
Upper right chamber, receives deoxygenated blood from the body
Right ventricle
Lower right chamber, pumps blood to the lungs
Left atrium
Upper left chamber, receives oxygenated blood from the lungs
Left ventricle
Lower left chamber, pumps blood to the body
Hematocrit
Red blood cell count
Diapedesis
Ability to squeeze through tiny pores in capillary walls and escape into tissues
Macrophage
White blood cell, large and versatile immune cell that acts as a microbe-devouring phagocyte, an antigen-presenting cell, and an important source of immune secretions
Clotting factors
Any of the factors in the blood whose actions are essential for blood coagulation
Hemophilia
Inherited bleeding disorder caused by low levels, or absence of, a blood protein that is essential for clotting
Universal donor
Blood type O negative
Universal recipient
Blood type AB postitive
A positive blood
Antigens A, Rh; antibodies B
B positive blood
Antigens B, Rh; antibodies A
AB positive blood
Antigens A, B, Rh; antibodies none
O positive blood
Antigens Rh; antibodies A, B
A negative blood
Antigens A; antibodies B, Rh
B negative blood
Antigens B; antibodies A, Rh
AB negative blood
Antigens A, B; antibodies Rh
O negative blood
Antigens none; antibodies A, B, Rh
Interatrial septum
Partition between the two atria, composed mostly of fibrous tissue
Interventricular septum
Partition between the two ventricles, composed mostly of myocardium
Atrioventricular valves
Valves that seperate atria and ventricles
Tricuspid valve
Seperates right atrium from right ventricle
Bicuspid valve
Seperates left atrium from left ventricle
Mitral valve
Bicuspid valve
Semilunar valves
Valves that seperate ventricles from blood vessels attatched to them
Pulmonary semilunar valve
Seperates right ventricle from pulmonary trunk
Aortic semilunar valve
Seperates left ventricle from aorta
Chordae tendineae
Strong chords that stretch from the edges of the tricuspid and mitral valve to the heart muscle and restrict how far the valve leaflets swing when they close
Cardiac cycle
Cycle involving periods of systole and diastole to fill and empty the chambers of the heart
Systole
Contraction of myocardium
Diastole
Relaxation of myocardium
Conduction pathway of the heart
Specialized strands of cardiac muscle tissue that coordinate rhythmic contractions of the heart
Sinoatrial node
Acts as the "pacemaker" of the heart, situated in the posterior wall of the right atrium
Atrioventricular bundle
Short bundle of fibers at the top of the interventricular septum that relay the nervous impulse from the atrioventricular node to the left and right ventricles
Bundle of His
Atrioventricular bundle
Bundle branches
Two branches that extend from the atrioventricular bundle and bring impulse down the interventricular septum
Purkinje fibers
Small fibers at the ends of the bundle branches that connect to and stimulate contraction of the myocardium
Cardiac output
Volume of blood pumped out of the heart per minute calculated by multiplying the stroke volume of the heart by the heart rate
Stroke volume
Volume of blood pumped out of the left ventricle every time it beats
Heart rate
Number of times the ventricles contract per minute
Coronary arteries
Blood vessels that take blood to the heart tissue
Coronary veins
Blood vessels that drain the heart tissue
Coronary sinus
Collects blood from the coronary veins
Bradycardia
Slow heart rate
Tachycardia
Fast heart rate
Arteries
Blood vessels that carry blood away from the heart
Arterioles
Small arteries
Veins
Blood vessels that carry blood toward the heart
Venules
Small veins
Capillaries
Small blood vessels that connect arterioles and venules where exchange of gases, nutrients, wastes and hormones takes place
Pulmonary vessels
All of the blood vessels that carry blood to and from the lungs
Systemic vessels
All of the blood vessels that carry blood to and from the body
Tunica externa
External layer of connective tissue
Tunica media
Middle layer made up of smooth muscle tissue
Tunica intima
Layer of squamous epithelial tissue that lines the lumen
Endothelium
Tunica intima
Lumen
Cavity in the vessel through which the blood flows