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Session 2 CM derm1

CM Derm-1- skin function & structure

What are the functions of the skin physical barrier immunological barrier UV protection Insulation temperature regulation Sensation
How does the skin regulate temperature through heat loss, evaporative and radiant heat loss
what are the 3 layers of skin epidermis dermis subcutaneous fat
What is contained in the dermis dermal nerves and vasculature
What are the cutaneous appendages hair follicles, glands, blood vessels
Stratified squamous epithelium made of basal, spinous, granular, stratum corneum epidermis
how often is the epidermis replaced every 28days
where is the epidermis attached attached to the dermis at the basement membrane zone
What two proteins do the cells of the epidermis contain keratin and melanin
What 3 specialty cells are found at the basal layer basal keratinocytes melanocytes merkel cells
columnar dividing cells that give rise to keratinocytes that move up through the layers of the skin to become corneocytes basal keratinocytes
Cells that synthesize pigment for UV protection melanocytes
Touch receptors in the basal layer merkel cells
Layer above the basal layer has keratinocytes and langerhans cells stratum spinosum
Cells held together by desmosomes that produce keratin keratinocytes
cells in the stratum spinosum that have immune function as APC's langerhans cells
Layer where keratinocytes become flat acquire more keratin and have granular cytoplasm stratum granulosum
skin layer where the keratinocytes are now dead and are corneocytes is 15-25 layers palms and soles are 100 layers thick form impermeable membrane shed continually stratum corneum
how many layers thick is stratum corneum at the soles and palms 100
Also known as the dermal-epidermal junction glues the epidermis to dermis basement membrane zone
layer of the skin that has blood vessels, nerves, skin appendages. Made of collagen and elstic fibers has histiocyets and mast cells dermis
what are the contents of the dermis connective tissue, nerves, sebaceous glands, hair follicles, blood vessels, meissner's corpuscles
What are the two sub-layers of the dermis papillary layer and reticular layer
sublayer of the dermis that supplies nutrients to the epidermis, regulates temperature due to an extensive vascular system. has a thin arrangement of collagen fibers papillary layer
thicker sublayer of the dermis that has thick collagen fibers arranged parallel to the skin surface. strengthens the skin and provides structure and elasticity. supports hair follicles, sweat glands and sebaceous glands reticular layer
Three types of cutaneous nerves free nerve endings pacinian corpuscles meissner's corpuscles
cutaneous nerve that senses pain, itch, temp, in the upper dermis free nerve endings
cutaneous nerve that senses pressure, in the subcutaneous layer pacinian corpuscle
cutaneous nerve that senses touch in the upper dermis meissner's corpuscle
where are the cutaneous blood vessels found what is their function subcutaneous layer and dermis provide nutrition and temperature regulation. Not found in epidermis
What is found in the subcutaneous tissue hair follicles, sweat glands, adipose tissue
What are the skin appendages eccrine sweat glands, apocrine sweat glands, hair follicles, sebaceous glands, nails
gland that is located in the dermis open to skin surface and helps regulate body temperature via sweat mostly found on palms and soles and axillae eccrine glands
True sweat glands that can produce up to two liters of sweat an hour. secrete mostly water eccrine glands
dermal gland in axilla, around genitalia, areola, nipples, eyelids, external ears. open directly into hair follicle. secrete with stress and sexual excitement source of body odor function after puberty apocrine sweat glands
What are the types of hair terminal hair, lanugo hair, vellus hair
thick pigmented hair found on scalp, beard, axillary, pubic areas. androgenically regulated terminal hair
fine hairs on the fetus lanugo hair
short fine nonpigmented hairs on much of the adult body. independent of androgens vellus hair
What is the hair growth cycle anagen, catagen, telogen
what is anagen phase of hair growth growth phase lasts 3 years 80-90% of scalp
what is catagen phase of hair growth involutional phase 3 weeks 1-2% of scalp
what is telogen phase of hair growth resting phase 3 months 10-20% of scalp once anagen begins again hair is shed
oil secreting gland attached to hair follicle small on trunk and extremities, large on breast face neck and upper chest absent on palms and soles sebaceous glands
what are the functions of sebum prevents drying, prevents evaporation, bacteriostatic
Hard, translucent dead keratin help in fine graspin and pinching protects the distal digits nails
how fast do fingernails grow .1 mm/day 6 months to replace
how fast do toenails grow .05 mm/day 12 months to replace
Created by: smaxsmith